Newsletter | August 13, 2026

08.13.26 -- Building A Self-Driving Lab For LNP Development

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Webinar: CAR-T for Relapsed/Refractory AML: From Discovery to First-in-Human Active Phase 1 Evaluation

Explore a novel anti-CD83 CAR-T strategy for relapsed/refractory AML with Dr. Marco Davila. Learn how targeting CD83 may overcome myelosuppression by selectively eliminating AML cells while sparing healthy stem cells. Discover the biology behind this approach, GMP manufacturing considerations, and insights from the first Phase 1 clinical trial evaluating this innovative cell therapy. Click here to learn more.

FOCUS ON MANUFACTURING

Building A Self-Driving Lab For LNP Development

With commercially available components, MIT researchers built a platform that accelerates LNP process development, optimization, and autonomous manufacturing research.

Barrel Filling Vs. Tip Filling A Syringe – Which Approach Should Be Used?

There are two primary filling methods for pre-filled syringes. Explore the pros and cons of each approach, highlighting why barrel filling is generally preferred in the pharmaceutical industry.

A Highly Productive, Chemically Defined Exosome Media System

See how chemically defined media and optimized bioreactor protocols increase exosome yields 40-fold while reducing commercial manufacturing costs from $10,000 to under $1,000 per dose.

The Scale-Up Of A Transient rAAV8 Production Process

New approaches to suspension cell culture and process scaling enable consistent, high-titer rAAV production. Gain insight into a clearer path to scalable manufacturing for gene therapy pipelines.

Effective Procurement Strategies For Labeling Systems In Drug Manufacturing

What is actually behind the procurement of a pharmaceutical labeling machine and how does the process work? You can find out here what the path to your pharmaceutical labeling machine looks like.

Smarter Cell Washing And Pre-Formulation For Allogeneic Therapies

Incomplete debris removal and manual steps often compromise allogeneic cell products. Review common processing bottlenecks and how modern preparation techniques prevent quality loss.

Evaluation Of Synthetic DNA As An Alternative To Plasmid DNA

Synthetic DNA offers a clear alternative to traditional plasmids in AAV manufacturing, cutting process contaminants, lowering variability, and streamlining commercial scale-up.

Rethinking Design, Cost, And Scalability In Biomanufacturing

Life science teams increasingly need tools that scale, simplify workflows, and reduce operational costs. Examine how emerging instrumentation focuses on usability, performance, and manufacturability.

Enhancing Host Cell DNA Testing With Digital PCR

Residual host cell DNA testing is evolving with digital PCR. Discover how streamlined methods improve accuracy, minimize manual steps, and support efficient biopharmaceutical manufacturing processes.

MANUFACTURING SOLUTIONS

Efficient Production Of MSCs And Exosomes - Terumo BCT

How To Best Optimize mRNA Production Workflows - Cytiva

Support Growth: A Solid Support Growth Material For Cell Culture - Eppendorf SE

Manufacturing Solutions For Your Cell And Gene Therapy Journey - Invetech

HEK293 Perfusion Strategy For Enhanced AAV And LV Production - FUJIFILM Biosciences

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