Newsletter | February 5, 2025

02.05.25 -- Breaking Barriers: Overcoming Immune Rejection In iPSC-Based Gene Therapy

SPONSOR

Discover the latest advancements in cell therapy supply chains! Join Cell & Gene Live as we explore cutting-edge automation, storage solutions, and cryopreservation techniques for iPSCs. Learn strategies to maintain cell viability, functionality, and therapeutic potential while enhancing long-term stability and clinical applicability. Don’t miss this opportunity to gain valuable insights from industry experts. Registration is free!

FOCUS ON TRANSLATIONAL RESEARCH

How To Overcome Immune Rejection In iPSC-based Gene Therapy

Even when induced pluripotent stem cells (iPSCs) are derived from the patient's cells, immune rejection can still occur. This article explores the causes as well as strategies to overcome immune rejection.

Adeno-Associated Virus: Enabling Genomic Medicine

Since the first rAAV-based therapy was approved by the FDA, application of gene therapies utilizing rAAV vectors has exploded and active clinical programs are being fast-tracked for clinical approval.

Maximize Your Gene Therapy Process With Genetic Analysis

Propel your gene therapy research to the forefront of discovery by incorporating genetic analysis into your investigations at any phase of the development process.

Assigning IR Absorption Bands For RNA Building Blocks

Explore the power of MMS in identifying RNA base signatures. This study analyzes vibrational modes of A, G, C, and U, revealing insights into electronic environments and molecular interactions.

Targeted LC-MS/MS Detection Of Lipid Impurities In Lipid Nanoparticles

Learn about an HPLC-MS/MS method for detecting lipid impurities in lipid nanoparticles (LNPs) and why it is critical for quality control of LNP-based drug delivery systems.

Epigenetics Application Guide

To fully understand biology and disease mechanisms, it is crucial to explore the role of epigenetic factors. Explore how epigenetic regulation works and methods to study these essential components.

Flow Cytometry Panel Design Fundamentals

Multicolor flow cytometry is a powerful technology that enables simultaneous analysis of multiple markers at the single-cell level. Read on to explore the flow cytometry panel design journey.

Gene Editing In Hematopoietic Stem Cells For Monogenic Blood Cell Diseases

Explore Cas9-mediated homology-directed repair and advancements in gene editing technologies that could significantly broaden the treatment possibilities for various blood disorders.

Queen Mary University Of London's Centre For Predictive In Vitro Models

Discover the future of in vitro modeling at the Queen Mary+Emulate Organs-on-Chips Centre and unlock new possibilities in the field of predictive medicine.

Lowering The Lipid Barrier To RNA-LNP Therapeutics

Industry experts discuss current and future trends, formulating successful lipid compositions and navigating the constantly evolving genomic medicine landscape.

Advances In Bioprocessing For Biologics And Gene Therapy Vectors

This article collection highlights the importance of continued research and development in the field of bioprocessing to revolutionize the next generation of therapies and personalized medicine.

Take Your CAR NK Cell Research To The Next Level

Discover all the tools you need to take your CAR NK cell research to the next level. Expand your CAR NK cells using a complete translational workflow.

TRANSLATIONAL RESEARCH SOLUTIONS

Accelerate Innovation In Life Sciences And Diagnostics - Invetech

INDe sgRNAs For Preclinical Safety, Toxicity, And Efficacy Studies - Synthego Corporation

One-Touch DNA, RNA, And Protein Quantitation In A Spectrophotometer - Danaher Life Sciences

Connect With Cell & Gene: