Automated Enrichment Of Human CD34+ Cells: CliniMACS Prodigy® HSC Enrichment System

High-quality CD34+ cell enrichment remains a foundational step in hematopoietic stem cell workflows, particularly when preparing starting material for downstream cell engineering applications. The HSC Enrichment process combines automated immunomagnetic labeling and separation to isolate CD34+ cells from mobilized leukapheresis products while supporting both standard- and large-scale manufacturing needs. With processing capacities of up to 1.2×10⁹ target cells and workflows completed in approximately 3–5.5 hours, the approach is designed to streamline cell processing while maintaining reproducibility and operational efficiency. Performance data demonstrate high CD34+ cell purity and viability, alongside substantial depletion of unwanted cell populations, helping manufacturers generate enriched cell products suitable for advanced research and development workflows.

For teams seeking to scale stem cell processing while reducing manual intervention, learn how this process offers a practical path toward consistent cell enrichment outcomes.