Addressing The Issue Of Genomic Stability In iPSCs: New Approach For Restoring Cell Lines

This webinar will explore the various types of quality control (QC) necessary for iPSCs, emphasizing the guidance from the International Society for Stem Cell Research (ISSCR) standards. Assessing genomic stability is a key aspect of QC, as up to 30 percent of cultures may exhibit genomic or genetic alterations that can impact their downstream applications in cell-based therapeutics.

The expert speakers highlight an innovative solution to these challenges designed to recover iPSC lines with mosaic genomic or genetic abnormalities. RESCUE, a novel solution from Cellected Ltd., utilizes high-throughput single-cell cloning along with the Advanced Instruments VIPS® PRO and rapid genomic screening to isolate normal cells from the population. The Cell Metric® X platform improves clone selection and growth analytics. When combined with custom functional QC, this approach allows for the swift return of a normal cell line to customers.

Watch to gain insight into the latest advancements in iPSC culture and quality control and how to take the initial step toward enhancing the reliability, consistency, and reproducibility of data, cell cultures, and assays.