Newsletter | March 27, 2025

03.27.25 -- A Practical Guide To Defining Priority Data In MES

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Introducing a new way to source solutions for improving, refining, and optimizing your CGT manufacturing! From April 8-10, Life Science Connect brings you the next virtual showcase from its network of trusted communities: Cell & Gene Therapy Tech Expo. Simply bring your attention, questions, and manufacturing requirements (no travel, cost, or inconvenience!) and experience this unique opportunity to learn about the latest technologies in CGT manufacturing and how they can help solve your biggest challenges.

FOCUS ON MANUFACTURING

A Practical Guide To Defining Priority Data In MES

Manufacturing execution systems (MES) play a crucial role in pharma/biotech, but MES platforms face the challenge of identifying the critical data that should be prioritized for supporting effective operations.

Starting With The End In Mind: Overcoming CGT Challenges

Explore insights from international experts on the rapidly growing CGT field. What are the challenges being faced? What trends are being seen? What are the future directions for cell and gene therapy?

Viruses And Viral Vectors, Are They Different?

Learn how effective disinfection solutions can ensure safety in pharmaceutical manufacturing by managing viral contaminants and enhancing patient protection.

Cleanroom Conceptual Design Paradigm

Gain insights into the nuances of cleanroom conceptual design for GMP operations and learn how an integrated approach can ensure regulatory compliance, functionality, and environmental performance.

The Paradigm Shift: From Scale-Up To Scale-Out In Genetic Medicine

The shift from "scale-up" to "scale-out" in genetic medicine enhances production speed, revolutionizing pharmaceutical manufacturing and accelerating life-saving therapies for global patient populations.

The Role Of Cell Culture Media Growth Factors

Growth factors in cell culture media are essential for cell survival and behavior. Uncover their diverse roles and the science behind choosing the right ones.

Resource Roadmap To Screening Success

Explore how tools streamline the development of cell-based therapies by optimizing processes, reducing costs, and accelerating manufacturing scalability. 

Advances In High-Throughput Upstream Process Development

Explore temperature effects on product titer, automated cell culture development workflow, maximizing product life-cycle efficiency with the right DOE strategy, and effective data management.

Overcoming Challenges In CGT Development

Explore connector solutions for sterility, chemical compatibility, and ultra-low temperature challenges when setting up a therapeutic process for long-term success.

Mixing Of Various Dry Powdered Media And Buffers

Explore how this mixing system efficiently handles various powdered media and buffers, ensuring precise solubilization and mixing in applications like cell culture and protein purification.

An End-To-End CAR-T Cell Therapy Development Partnership

This advanced tool offers a reliable and scalable solution to the numerous workflow challenges faced in the CAR-T cell therapy landscape.

Depth Filtration Devices

Devices containing depth media filters are typically more efficient. Browse these products and devices for the downstream processing of cell culture solutions, fermentation broths, and lysates.

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The London Biotechnology Show, taking place at ExCeL London on 18-19 June, is a premier event driving advancements in biotechnology for the medical and healthcare sectors. Serving as a global platform, it unites industry leaders to foster innovation, collaboration, and progress. With a focus on transformative breakthroughs, the event aims to accelerate the impact of biotechnology in the UK and worldwide. Register now

MANUFACTURING SOLUTIONS

A Scaled-Down Solution For Simple, Robust Upstream Intensification - Repligen

Fully Customizable Central Command Console For Cleanrooms: VLADS - Germfree

Ready-To-Use Nested Vials - West Pharmaceutical Services, Inc.

A Pilot-Scale, Sedimenting Centrifuge - CARR Biosystems

Biopharmaceutical Services - Cytiva

Medium For High AAV Titers Across Multiple HEK293 Cell Lines - MilliporeSigma

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