10.29.24 -- A "Particular" Problem For Cell Therapy Products, Part 2: Cell Clumps And Other Inherent Particles

Learn how researchers are leveraging CRISPR nucleases, employing single-cell cloning techniques, optimizing delivery methods, and refining guide RNA design to enhance the safety and efficacy of iPSCs.

Discover how osmolality can be applied throughout the bioprocessing workflow for RNA, and recognize the importance of this sensitive measurement, from formulation to cryopreservation.

Choosing the right container closure system (CCS) format is crucial, so understanding the different parts involved, their functions, storage requirements, and how they impact administering the drug is essential.

Insights from real-world case studies show how to optimize AAV manufacturing with a transfection reagent and enhancer platform that boosts titers and percent full capsids by 2- to 10-fold.

Understand the advantages of non-viral transfection technologies for CRISPR- or transposon-based genetic modification CGT and how an improved electroporation technology can support this approach.

Adopt cloud-based Vault LIMS to streamline QC operations, enhance data accessibility, and align with broader IT and business strategies.

High Throughput Screening (HTS) chromatography tools accelerate process development and reduce material use but are less common in some modalities due to sample limits and required expertise.

Explore a platform that addresses five critical pain points to help mRNA manufacturers flexibly scale while improving the digital maturity of their sites.