A Multi-Attribute Analysis CE Platform To Assess Identity And Titer Of Lentiviral Vectors

By Chris Heger, Ph.D., Director of Applications Science for the Analytical Solutions Division of Bio-Techne

Lentiviral vectors (LVVs) have multiple properties that make them well suited for cell and gene therapy applications: they can infect a wide range of cells, integrate into target cell genomes, and carry a large transgene. However, the continued expansion and success of LVVs in cell and gene therapies requires improved analytical platform methods for their assessment and manufacturing. It is crucial to examine the current analytical challenges of LVVs and explore new, robust solutions to address them.

One strategy to increase efficiency while reducing time and resources is moving to a multi-attribute analysis platform like Maurice that can rapidly provide high-quality data on purity, identity, stability, and titer. A streamlined platform can produce better results, free up lab real estate, and reduce sample consumption and capital investment. Download the complete article to learn more about how collaborating with a streamlined platform partner can yield an efficient, personalized method that is well-suited for your process goals.