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REGULATIONS AND COMPLIANCE

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mRNA For Cancer Immunotherapy 2024 Outlook | Audience Q&A

During our Cell & Gene Live, mRNA For Cancer Immunotherapy 2024 Outlook, our expert panelists answered audience questions regarding patient safety, foreseeable challenges in mRNA cancer immunotherapy for solid tumors, and much more.

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Tackling Cell And Gene Therapies' Top 3 Regulatory Impediments: Audience Q&A

During each Cell & Gene Live, our audience has the opportunity to submit real-time questions for our expert panelists. Watch and listen as Nina Hunter, Ph.D., VP Corporate Strategy at REGENXBIO and Adora Ndu, PharmD, JD, Chief Regulatory Affairs Officer at BridgeBio p...

15:18 Cell and Gene Tech Expo
Mitigate Clinical Risk In Cell Therapy Development With A GMP Compliant Process

Help shape the future of medicine by building better, safer cell therapies. See how expertise in scalable, GMP-compliant cell engineering can effectively mitigate clinical development risks.

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CGT's Main Opportunities To Meet Regulatory Requirements

Host and Moderator, Erin Harris, Chief Editor of Cell & Gene, began this Cell & Gene Live, Tackling Cell and Gene Therapies’ Top 3 Regulatory Impediments, featuring Nina Hunter, Ph.D., VP Corporate Strategy at REGENXBIO and Adora Ndu, PharmD, JD, Chief Regul...

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Challenge #3: Lack Of Animal Models

Many cell and gene therapies are intended for diseases and conditions that primarily impact pediatric patients, requiring the prospect of direct benefit to individual subjects enrolled in the trial.  In the absence of good animal models, there may be challenges demon...

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Why Clinical Requirements Change: Dr. Peter Marks on Pre-IND Meeting Pathways

Learn how clinical requirements change after the FDA and a company agree on a pathway during a pre-IND meeting and how the company might recover as a result.

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Challenge #2: Rare Or Ultra-Rare Study Design Considerations And Use Of Existing Data

There are more than 7,000 unique, rare diseases recognized in the United States, and 300 million people worldwide living with a rare disease; patients often experience a long journey to receive their diagnosis. Our expert panelists, Nina Hunter, Ph.D., VP Corporate Strate...

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How The FDA's 2024 Draft Guidances Will Influence CGT Regulation In 2025

Kimberly Benton, Ph.D., Master Principal and Head of Regulatory at Dark Horse Consulting and Bambi Grilley, RPh, RAC, CIP, CCRC, CCRP, Director, Clinical Research and Early Product Development Center for Cell and Gene Therapy, Professor of Pediatrics Baylor College of Med...

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Executive Roundtable: Cell Therapy Predictions For 2025 And Beyond

In this executive roundtable discussion, Bioprocess Online editor Tyler Menichiello is joined by CEO, co-founder, and president of Ossium Health, Kevin Caldwell, CSO of FibroBiologics, Hamid Khoja, Ph.D., and president and acting CEO of Triumvira Immunologics, Ro...

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How The New Administration Could Shape FDA Oversight, Compliance, And Guidance In 2025

Kimberly Benton, Ph.D., Master Principal and Head of Regulatory at Dark Horse Consulting and Bambi Grilley, RPh, RAC, CIP, CCRC, CCRP, Director, Clinical Research and Early Product Development Center for Cell and Gene Therapy, Professor of Pediatrics Baylor College of Med...

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How Past Gene Therapy Approvals Are Shaping the Future with Dr. Peter Marks

In this segment of Cell & Gene Live, Dr. Peter Marks shared what he and his team have learned from current gene therapy approvals to accelerate future approvals.

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A Straightforward Path Toward Regulatory Compliance & Data Integrity With Your Microbial Testing Systems

In this webinar, we will share a variety of strategies for implementing and validating microbial identification systems in the cGMP environment, possible difficulties along the way, and a comprehensive solution that addresses these challenges.

6:26 Making USP Guidance Actionable for CGT Materials
Making USP Guidance Actionable For CGT Materials

In this segment of Cell & Gene Live, Anthony Blaszczyk, Ph.D., Senior Scientist at the U.S. Pharmacopeia, and Basak Clements, Ph.D., Founder and Senior Advisor at biomatria, were joined by Cell & Gene Chief Editor Erin Harris to discuss USP’s Cell & Gene...

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Patient Data's Impact On CMC Robustness

When CGT products demonstrate dramatic improvements with minimal safety concerns in a Phase 2 study, sponsors may want to modify the protocol mid-study to increase patient enrollment.

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Assessing Residuals In Processing And Fill/Finish For iPSCs

In this segment of Cell & Gene Live, Optimizing Storage Solutions for iPSCs, our expert panelists, Pratik Jaluria, Ph.D., SVP Technical Development Strategy at BlueRock Therapeutics, Bruno Marques, Ph.D. VP, Process and Product Development at Century Therapeutics, and...

15:32 Cell And Gene Therapy Innovations
Cell And Gene Therapy Innovations

This interview with a pharmaceutical analytics expert discusses key insights into advances in cell and gene therapy and the strategies used to support customers in improving their therapeutic development.

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Strategies To Reduce Regulatory Risks In Gene Therapy

Learn how to mitigate regulatory risk for your gene therapy process.

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Race To The Regulatory Finish Line: Dr. Nicole Verdun Talks Efficiencies In Platform Technologies

Could a platform approach help certain therapies make their way over the regulatory finish line more efficiently?

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What's New for 2024: Dr. Nicole Verdun Offers a Look Inside The Office Of Therapeutic Products

What is the Office of Therapeutic Products, where did it originate, and what's on its regulatory agenda for 2024?

1:59 A CDMO Perspective Bioprocess Automation And Data Management
A CDMO Perspective: Bioprocess Automation And Data Management

Watch this video to understand data management and process automation challenges across single-use bioprocessing applications from a CDMO leader, Paul Jorjorian, VP and GM of Pharma Services at Thermo Fisher Scientific.

1:42 Regulatory expertise
Regulatory And Biosafety Testing Expertise

Advancing biologics requires confidence in safety, quality, and compliance. Learn how integrated analytical and biosafety testing, backed by decades of expertise, helps reduce risk.

6:44 Bridging Analytical Gaps to Ensure CGT Material Quality
Bridging Analytical Gaps To Ensure CGT Material Quality

In this segment of Cell & Gene Live, "Materials Matter: Ensuring Quality of CGT Materials," Cell & Gene Chief Editor Erin Harris was joined by Anthony Blaszczyk, Ph.D., Senior Scientist at the U.S. Pharmacopeia, and Basak Clements, Ph.D., Founder and Sen...

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Congruence And Divergence In Global Regulatory Approvals

Kimberly Benton, Ph.D., Master Principal and Head of Regulatory at Dark Horse Consulting and Bambi Grilley, RPh, RAC, CIP, CCRC, CCRP, Director, Clinical Research and Early Product Development Center for Cell and Gene Therapy, Professor of Pediatrics Baylor College of Med...

7:00 Future Proof Process Design Through Risk-Focused Decisions, Automation Readiness, And Regulatory Pragmatism
Future Proof Process Design Through Risk-Focused Decisions, Automation Readiness, And Regulatory Pragmatism

In this segment of Cell & Gene Live, Designing Early Manufacturing For Long-Term Success In CGT, Raymond Luke, Senior Director of MSAT at Verismo Therapeutics and Todd Luman, Executive Director of Process and Product Development at Allogene share that future proofing ...

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Key Regulatory Challenges, Innovations, And Opportunities For CGT In 2025

Kimberly Benton, Ph.D., Master Principal and Head of Regulatory at Dark Horse Consulting and Bambi Grilley, RPh, RAC, CIP, CCRC, CCRP, Director, Clinical Research and Early Product Development Center for Cell and Gene Therapy, Professor of Pediatrics Baylor College of Med...

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How The FDA Strengthens Industry Collaboration

Kimberly Benton, Ph.D., Master Principal and Head of Regulatory at Dark Horse Consulting and Bambi Grilley, RPh, RAC, CIP, CCRC, CCRP, Director, Clinical Research and Early Product Development Center for Cell and Gene Therapy, Professor of Pediatrics Baylor College of Med...

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MilliporeSigma Bio-Expo Live February 2025: Upstream Bioprocessing

Review the benefits of implementing a closed and sterile sampling system, such as NovaSeptum®, to improve sampling procedures and meet regulatory expectations.

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Navigating Global Regulations, Equity Challenges, And The Future Of Patient Access

Kimberly Benton, Ph.D., Master Principal and Head of Regulatory at Dark Horse Consulting and Bambi Grilley, RPh, RAC, CIP, CCRC, CCRP, Director, Clinical Research and Early Product Development Center for Cell and Gene Therapy, Professor of Pediatrics Baylor College of Med...

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Regulatory Challenges And Future Outlook For iPSC Therapies

In this part of our discussion during the Cell & Gene Live, Unlocking the Potential of iPSC Therapies in Regenerative Medicine, Julie Allickson, Ph.D., Chief Technology Officer at Mayo Clinic's Center for Regenerative Biotherapeutics and Erin Kimbrel, Ph.D., Head ...

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Lower Variability For Viral Titer Determination

Learn about the benefits of ddPCR for ensuring precise and reproducible viral titers in the development of effective adeno-associated virus AAV-based gene therapies.