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REGULATORY GUIDANCE AND ENABLING COMPLIANCE

4:00 24_01_CGL_FDA_Webinar_Seg03-min
Focal Points for 2024: Dr. Verdun and Dr. Marks Talk Regulatory Challenges for Cell-Based Therapies

Dr. Verdun and Dr. Marks provide detailed feedback on the regulatory challenges facing cell therapy and explain the Agency’s most important focal points for 2024, patient accessibility, and more.

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How The New Administration Could Shape FDA Oversight, Compliance, And Guidance In 2025

Kimberly Benton, Ph.D., Master Principal and Head of Regulatory at Dark Horse Consulting and Bambi Grilley, RPh, RAC, CIP, CCRC, CCRP, Director, Clinical Research and Early Product Development Center for Cell and Gene Therapy, Professor of Pediatrics Baylor College of Med...

4:24 Interview With Pharma Analytics Field Application Specialist - Sandi True
Interview With Pharma Analytics Field Application Specialist - Sandi True

Hear Sandi True, a Field Applications Specialist discuss helping customers navigate challenges often encountered when evaluating and implementing Residual DNA Quantitation, Mycoplasma Detection, and Microbial Identification Assays.

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Key Regulatory Challenges, Innovations, And Opportunities For CGT In 2025

Kimberly Benton, Ph.D., Master Principal and Head of Regulatory at Dark Horse Consulting and Bambi Grilley, RPh, RAC, CIP, CCRC, CCRP, Director, Clinical Research and Early Product Development Center for Cell and Gene Therapy, Professor of Pediatrics Baylor College of Med...

43:42 Simple In-House Mycoplasma Testing Method
Simple In-House Mycoplasma Testing Method For Regulatory Expectations And Rapid, Confident, And Actionable Results

In this webinar, we present an overview of worldwide regulatory guidance for mycoplasma testing, as well as a mycoplasma testing method that has been accepted by regulatory authorities worldwide across various therapeutic modalities.

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Defining The CMC / Clinical Relationship For Allogeneic Cell Therapies

During this segment, Nguyen and Wagner define why the relationship between CMC and Clinical is so critical, and they also explain what a mutually beneficial partnership between CMC and Clinical looks like.

3:22 24_01_CGL_FDA_Webinar_Seg11-min
Understanding AI And Machine Learning's Impact On CGT with Dr. Peter Marks and Dr. Nicole Verdun

During this segment, Dr. Peter Marks and Dr. Nicole Verdun share their take on how AI and machine learning will impact FDA regulation in 2024.

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mRNA For Cancer Immunotherapy 2024 Outlook | Audience Q&A

During our Cell & Gene Live, mRNA For Cancer Immunotherapy 2024 Outlook, our expert panelists answered audience questions regarding patient safety, foreseeable challenges in mRNA cancer immunotherapy for solid tumors, and much more.

1:03:39 Rapid Micro Methods In QC Micro Testing
Rapid Micro Methods In QC Micro Testing: A NIBRT Perspective

Learn about some of the advanced Rapid Micro Method systems that are being adopted by biopharma companies worldwide, and how they are changing the face of QC Microbiological testing.

2:36 24_01_CGL_FDA_Webinar_Seg05-min
Why Clinical Requirements Change: Dr. Peter Marks on Pre-IND Meeting Pathways

Learn how clinical requirements change after the FDA and a company agree on a pathway during a pre-IND meeting and how the company might recover as a result.

27:51 Thermo Roundtable screenshot
Quality Roundtable: Optimizing Biologics Manufacturing Processes With Raw Materials

Improve your commercial manufacturing process with advice from regulatory and raw materials experts on the development journey from pre-clinical to licensure.

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Innovative Contamination Control: Enabling Integrity And Efficiency

An integrated approach can enhance contamination control, boost process efficiency, and ensure the production of high-quality cell therapy products.

2:39 resdnaseq workflow
ResDNASEQ Workflow Solution

Explore the Applied Biosystems resDNASEQ workflow solutions. Starting with the sample preparation kit, to purification, quantitating residual host-cell DNA, and analyzing resDNASEQ assays.

3:44 Sandi True
Interview With Nico Chow And Sandi True, Field Applications Specialists

Hear Nico Chow and Sandi True, Field Applications Specialists, discuss working with customers to help them evaluate and implement Residual DNA Quantitation, Mycoplasma Detection, and Microbial Identification Assays.

15:32 Cell And Gene Therapy Innovations
Cell And Gene Therapy Innovations

This interview with a pharmaceutical analytics expert discusses key insights into advances in cell and gene therapy and the strategies used to support customers in improving their therapeutic development.

1:59 24_01_CGL_FDA_Webinar_Seg07-min
Patient Data's Impact On CMC Robustness

When CGT products demonstrate dramatic improvements with minimal safety concerns in a Phase 2 study, sponsors may want to modify the protocol mid-study to increase patient enrollment.

43:12 Successful Microbial Testing And Identification
Successful Microbial Testing And Identification

In this presentation, one of our industry-leading customers discusses how they've successfully implemented the Applied Biosystems MicroSEQ Microbial Identification System in their laboratory testing.

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Challenge #2: Rare Or Ultra-Rare Study Design Considerations And Use Of Existing Data

There are more than 7,000 unique, rare diseases recognized in the United States, and 300 million people worldwide living with a rare disease; patients often experience a long journey to receive their diagnosis. Our expert panelists, Nina Hunter, Ph.D., VP Corporate Strate...

2:10 24_01_CGL_FDA_Webinar_Seg08-min
CMC Comparability: Transitioning to Commercial Manufacturing with Dr. Nicole Verdun

In this segment, Dr. Nicole Verdun shares some of the challenges demonstrating CMC comparability during late-stage product development (i.e., pivotal or Phase 3 clinical trial) that occur while transitioning to commercial manufacturing.

38:24 Path Toward Regulatory Compliance And Data Integrity With Microbial Testing
A Straightforward Path Toward Regulatory Compliance, Data Integrity, And Computer Systems Validation

Learn practical strategies for validating microbial identification systems in cGMP. Understand regulatory guidance and master a complete Computer Systems Validation plan for full compliance.

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Major Trends Impacting Allogeneic Cell Therapies For Oncology

We kicked off this Cell & Gene Live, Unlocking the Future of Allogeneic Cell Therapy for Oncology by discussing the major trends impacting allogeneic cell therapies for oncology.

3:31 24_01_CGL_FDA_Webinar_Seg01-min
What's New for 2024: Dr. Nicole Verdun Offers a Look Inside The Office Of Therapeutic Products

What is the Office of Therapeutic Products, where did it originate, and what's on its regulatory agenda for 2024?

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Navigating Global Regulations, Equity Challenges, And The Future Of Patient Access

Kimberly Benton, Ph.D., Master Principal and Head of Regulatory at Dark Horse Consulting and Bambi Grilley, RPh, RAC, CIP, CCRC, CCRP, Director, Clinical Research and Early Product Development Center for Cell and Gene Therapy, Professor of Pediatrics Baylor College of Med...

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Challenge #3: Lack Of Animal Models

Many cell and gene therapies are intended for diseases and conditions that primarily impact pediatric patients, requiring the prospect of direct benefit to individual subjects enrolled in the trial.  In the absence of good animal models, there may be challenges demon...

24:19 Maximize Quality Assurance Through Rapid Sterility Testing
Maximize Quality Assurance Through Rapid Sterility Testing

This webinar explores mitigating the risk of product loss, and production delays, as well as the critical role rapid sterility testing plays in ensuring the quality and safety of cell therapy products.

57:25 Microbial Identification Via DNA-Seq
Microbial Identification Via DNA-Seq

Learn how DNA sequencing-based microbial identification supports regulatory compliance and enhances contamination control in critical environments.

8:44 24_01_CGL_FDA_Webinar_Seg13-min
2024 Regulatory Outlook With Dr. Peter Marks And Dr. Nicole Verdun | Audience Q&A

Experts on the Cell & Gene Live event, 2024 Regulatory Outlook, answer questions about topics including pediatric development in rare diseases, diversity planning for ultra-rare disease, anticipated approvals by 2025, and more.

58:03 Thermo - CAR-T Innovation
CAR-T Innovation: Balancing Allogeneic And Autologous Cell Therapy

Join experts as they discuss strategies for optimizing allogeneic and autologous therapies, aiming for balanced development and wider patient accessibility by 2030.

27:52 Thermo - Regulatory webinar
Navigating Global Regulatory Landscapes In An Evolving Biopharma Industry

Minimize regulatory risks and ensure compliance in the evolving biopharma sector. Watch this on-demand discussion for insights on change management, supplier collaboration, and future market trends.

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Best Practices For Effective Donor Management

Starting with high quality donor material is critical for allogeneic cell therapy drug manufacturing, and this requires laying the groundwork for a high-touch, end-to-end donor pool management strategy.