ABOUT SYNTHEGO
Synthego is a genome engineering company that enables life science research and therapy development with a mission of increased access to engineered therapies for all patients. With unparalleled CRISPR expertise, state-of-the-art GMP capabilities, and a continuum of product offerings, Synthego supports CRISPR-edited cell and gene therapeutic development at every step, from R&D through IND submission to first-in-human trials.
FEATURED CONTENT
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![GettyImages-624034258 chemical mixing]( "Demystifying CRISPR gRNA Chemical Modifications")
Chemical modifications on CRISPR gRNAs enhance stability, editing efficiency, and reduce immune responses, enabling in vivo applications and clinical success.
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![CRISPR Gene Editing]( "Unlocking The IP Benefits Of Novel Nucleases In CRISPR Therapies")
Incorporating novel nucleases into CRISPR therapies enhances intellectual property benefits through improved licensing, strategic protections, and access to new gene targets.
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![Guidance-Puzzle-Regulatory-iStock-489087670]( "CMC And Regulatory Considerations For CRISPR Therapies")
This article explores the details of Chemistry, Manufacturing, and Controls and Critical Quality Attributes, which play an important role in gene editing.
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![GettyImages-1366661187 cell tech]( "CRISPR Clinical Trials To Follow In 2024 And Beyond")
CRISPR therapies are being developed for genetic disorders, cancer, and infectious diseases. Explore which CRISPR clinical trials are worth keeping an eye on this year.
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![Crispr gene editing-GettyImages-1139760176]( "CRISPR 101 - Your Guide To Understanding CRISPR")
Review the fundamentals of CRISPR technology, development, and its use to manipulate genes in different ways, such as altering their nucleotide sequences or changing their expression.
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![CRISPR Gene Editing]( "CRISPR Clinical Trials And Regulatory Approval Of CRISPR Therapy Drugs")
Navigate the intricate regulatory landscape with knowledge that can help you move your CRISPR therapies quickly and efficiently through clinical trials.
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![GettyImages-1445640967 RNA therapy]( "CRISPR In The Clinic: Regulatory Experts Discuss Development Of Cell And Gene Therapies")
A regulatory expert provides her insight on what regulatory experts do and how they can help you accelerate your path from bench to clinic.
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![Synthego sgrna bucket]( "CRISPR sgRNA For Successful Gene Editing: Discovery To Clinic")
The single guide RNA (sgRNA) is one of the key components of successful CRISPR gene editing. Here we cover all the important aspects of sgRNA and Synthego’s sgRNA products.
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![GettyImages- 1180547354 trial data]( "Understanding CRISPR Clinical Trials: Your Questions Answered")
CRISPR technology is revolutionizing cell and gene therapies, but how do CRISPR clinical trials work? Follow this explanation of CRISPR therapies from the discovery phase to FDA approval.
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![Gene Therapy iStock-1291142726]( "Key Challenges for CRISPR In Clinical Development")
Learn how to approach CRISPR cell and gene therapy development challenges, such as regulatory hurdles, ensuring consistency, finding qualified and experienced staff, and obtaining GMP-Grade reagents.
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![GettyImages-958260280-genetic-engineering-genome-editing-helix-dna]( "Understanding FDA Cell And Gene Therapy Guidance")
Grow your understanding of how new developments in CRISPR gene therapy drugs and FDA guidance are affecting cell and gene therapy products.
VIDEOS
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![Synthego - CRISPR]( "Enabling GMP Production Of sgRNA For CRISPR-Based Cell And Gene Therapies")
Explore critical steps and key regulatory requirements for developing CRISPR therapeutics and gain practical advice on how to avoid common pitfalls.
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![GettyImages-508496956-dna]( "A Novel Nuclease For CRISPR-Based Cell And Gene Therapies")
Take an exploration of the therapeutic potential of hfCas12Max, showcasing its advantages over existing CRISPR nucleases and its role in accelerating the development of life-saving treatments.
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![Gene therapy iStock-1177162185]( "Moving CRISPR Therapies From Research To The Clinic")
Professor Stephanie Cherqui shares her thoughts on taking CRISPR-based therapies from research to the clinic, the upcoming trials she is working on, and more.
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![synthego suites]( "Next Generation GMP Facility For CRISPR Based Therapies")
Explore a state-of-the-art GMP facility focused on CRISPR based Cell and Gene therapies with helping temperature controlled warehouse and multiple synthesis suites.
CONTACT INFORMATION
Synthego Corporation
3696 Haven Ave, Suite A
Redwood City, CA 94063
UNITED STATES
Phone: 888-622-6883
Contact: Meenakshi Prabhune
FEATURED PRODUCTS
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![GettyImages-1480892977-doctor-gene-dna-brain-lungs-heart]( "High-Fidelity Nuclease For Therapeutic Breakthroughs")
The hfCas12Max nuclease offers superior gene editing with high fidelity, broad PAM recognition, minimal off-target effects, and compatibility across cell types for therapeutic applications.
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![Guidance-Puzzle-Regulatory-iStock-489087670]( "CRISPR Therapeutic Regulatory Expertise And Support")
Explore regulatory support services that can help you successfully to navigate CRISPR-based therapeutic development and prepare you for a successful IND submission.
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![GettyImages-1294339662-lab-cleanroom-computer]( "GMP sgRNA Manufacturing")
Transition from early-phase research through process development into the clinic with these continuum sgRNA available in different grades.
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![3 Cleanroom Scientists GettyImages-1301319238]( "INDe sgRNAs For Preclinical Safety, Toxicity, And Efficacy Studies")
Seamlessly transition from discovery to delivery with INDe sgRNAs. These quality sgRNAs can be synthesized in quantities from milligrams to grams and follow high purity specifications.
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![Synthego synthetic sgRNA]( "Synthetic Research Grade sgRNA Manufacturing For CRISPR Experiments")
Consistently achieve high editing efficiency and quick turnaround time in as little as 7 days with synthetic sgRNA that pave your way to a successful CRISPR experiment.
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![Synthego facility]( "New Next-Generation GMP Facility")
A new state-of-the-art GMP facility has been created to accelerate the development of CRISPR-based cell and gene therapies, overcoming challenges such as procuring reliable GMP-grade sgRNA persist.
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![Partners-Getty- 871491468]( "High Quality Clinical Grade sgRNA For CRISPR Based Therapies")
Learn about three different grades of high-quality synthetic sgRNAs that will help support every step of your CRISPR-based therapy development process.
