Learn why particulate levels and minimizing contamination are important for single-use systems and compare single use system bags.

Learn about the three most common sources of filtration failures and how to prevent these problems.

Learn about large and small volume parenteral injectable drugs, their comparative sizes, types, sterilization processes, and applications.

The FDA holds strict requirements for magnetic bead removal prior to therapeutic use. Learn how this system effectively separates cells from microcarriers and provides maximum cell recovery.

Examine the single-use supply constraints interfering with bioprocess operations that have been exacerbated by the COVID-19 pandemic, along with one company's solution to help minimize production delays.

Freezing biologics is a complex undertaking. As more biotherapies enter the market, ensuring manufacturers have the technology to optimize their cold chain applications is paramount.

The need for low-temperature storage capable of surmounting the molecular and logistical challenges associated with these treatments has become core to achieving commercial-scale production.

We investigate material adsorption of mRNA-encapsulated lipid nanoparticle (LNP) formulation comparing the Aramus fluoropolymer bag to commonly used glass vials and polypropylene (PP) cryotubes.

This application note explains the use a liquid particle counter to qualify the cleanliness of single-use 2D bag assemblies.

New single-layer assemblies, made without the curing agents, antioxidants, plasticizers, or adhesives that represent potential contamination sources, may offer companies a safer, more efficient choice.

This application note reviews the chemical compatibility of Aramus™ assemblies with dimethyl sulfoxide (DMSO), which is commonly used as a cryopreservant in the cell and gene therapy (CGT) markets.

This application note explores the cryogenic temperature compatibility of the Aramus™ bag assembly material through freezing and drop testing after 24-hour minimum immersion in the liquid nitrogen (LN2) vapor phase.

This application note demonstrates how the Nicomp Z3000 system is ideally suited for determining size and zeta potential of gold nanoparticles.

Understanding the cold chain supply scale-up challenges that can threaten product integrity empowers manufacturers to implement efficient, cost-effective solutions.

The size and surface charge of liposomes—spherical engineered particles made of phospholipids—are important characteristics that require measurement and monitoring in biopharmaceutical applications. 

This paper helps to define nanoparticles, their various uses, and the analytical techniques used for their physical characterization.

This paper will discuss the results of applying an approach using sensors and more suitable material to a frozen shipping study of single-use fluoropolymer bags.

This paper is intended to help those new to particle size analysis understand each technique’s various strengths and weaknesses in order to select the proper technique for their samples.

This application note demonstrates the capabilty of advanced, automated systems for subvisible particle testing in injections, ophthalmic solutions, and lipid emulsions. 

This paper explains how single-use bags perform during freezing, storage, and thawing steps and why they present an efficient alternative to vials in a variety of upstream cell banking applications.

Watch how our single-use mixing system creates a completely sterile mixing and recirculation process, ensuring your buffer and media are mixed correctly and efficiently.

Ross Acucena, applications director, and Donnie Beers, product manager, introduce our single-use mixing system made to be deployed rapidly to help manufacturers meet development, supply, and cost objectives.

Ross Acucena, applications director, and Donnie Beers, product manager, introduce our highly functional and adaptable microcarrier cell separation bags designed for single-use processes. 

This webinar focuses on how filtration manufacturers optimize materials for performance and integration within single-use systems.

Learn how utilizing high-density cell banking workflows in combination with your already intensified upstream process can further enhance your process productivity while reducing contamination risks.

Learn about particle sizing methodology, equipment, software, and compliance to meet USP standards for parenteral drug manufacture, proteins, ophthalmic solutions and lipid emulsions.

Entegris' Joy Xiaohui Chen and Cari Sadowski of Fujifilm Diosynth Biotechnologies evaluate single-use bag material interaction and adsorptive relationship with AAV viral vector during storage.

Learn more about the uncertainties and complexities encountered when expanding the application of single-use technologies (SUT) in cryogenic bioprocesses.

Study data shows the utility of low temperature suitable materials and packaging,  sensors for monitoring shipments, and qualification and evaluation through simulated standards and real-world transit.

How high-density cell banking accelerates upstream processes by providing a larger volume of concentrated cells at the start of a production run, shortening seed training from weeks to days. 

Explore the needs and requirements of equipment and processes to handle lower temperatures, incuding a complete, cold-resistant solution of bags, tubing, connectors, and shells for freeze/ship/thaw processes.

This video shows examples of the performance of Aramus™ film, polyethylene, and polyolefin film when subjected to cold temperatures.

Janelle Rupkalvis from Entegris Life Sciences describes the options, technologies and suppliers for single use assemblies in low temp bioprocessing.

Janelle Rupkalvis describes the process and options for ordering single use assemblies from Entegris Life Science.

Mike Johnson from Entegris and Johannes Kirchmair from Single Use Support explain the importance of having a complete, cold-resistant solution of bags, tubing, connectors, and shells.