FEATURED ARTICLES

• Improving Gene Therapy Development With Organ-On-A-Chip Technology

  Explore the current challenges of developing gene therapies, the potential of Organ-on-a-Chip technology, the future of gene therapy, and more.

• Customer Spotlight: Queen Mary University Of London's Centre For Predictive In Vitro Models

  Discover the future of in vitro modeling at the Queen Mary+Emulate Organs-on-Chips Centre and unlock new possibilities in the field of predictive medicine.

• Emulate Endorses The FDA Modernization Act Of 2021

  Learn why removing the mandate for animal testing would enable faster, more efficient, and more humane drug development, all while benefiting both patients and the pharmaceutical industry.

• An Introduction To Organ-On-A-Chip Technology

  Discover how Organ-on-a-Chip technology revolutionizes drug development, overcoming the limitations of traditional models to create more accurate, efficient pathways to life-saving treatments.

• The Future Of Preclinical Animal Models In Drug Discovery

  The paradigm shift from animal to human Organ-Chips in preclinical research offers promising insights and efficiencies, crucial for advancing drug development and reducing human suffering.

• Evaluating CAR T-Cell Therapy Vascular Recruitment, Trafficking, And Killing

  Learn about a more human-relevant platform that enables researchers to assess the trafficking and killing efficiency of immunotherapy as well as the proof-of-concept of immuno-oncology co-therapy.

• Designing The Human Emulation System

  Examine how the Human Emulation System merges cutting-edge Organ-on-a-Chip technology with user-friendly design, paving the way for seamless experimentation and deeper insights into human biology.

• Evaluating On-Target/Off-Tumor Effects Of Cancer Immunotherapies

  A promising class of engineered T-cell engaging bispecific antibodies (TCBs) is revolutionizing cancer treatment, but safety concerns persist. Organs-on-Chips offer a human-relevant solution.

• Exploring Neuroinflammation, Neurodegeneration With A Brain Organ-Chip

  Examine how Organ-on-a-Chip technology, accurately mimicking human neuroinflammation, offers promising human-relevant avenues for neurodegenerative disease research and therapeutic development.

• Studying Gut Inflammation And Barrier Disruption With Organ-On-A-Chip Technology

  See how the Colon Intestine-Chip has been employed to model cytokine-mediated inflammation and barrier disruption in the intestine.

• Recapitulating Inflammation: How To Use the Colon Intestine-Chip To Study Complex Mechanisms Of IBD

  To address the challenges associated with conventional drug development models, a Colon Intestine-Chip has been developed to recapitulate the biology that drives inflammatory bowel disease.

• Predicting Human Liver Damage With A More Accurate In Vitro Hepatotoxicity Assay

  This study explores whether a species-specific, multicellular, in vitro hepatotoxicity assays utilizing Liver-Chips can provide a greater understanding of hepatotoxicity mechanisms than animal models.

• Investigating Key Mechanisms Of Parkinson's With A Brain-On-A-Chip

  Efforts to develop a dynamic “brain-on-a-chip” model that closely resembles the human substantia nigra could be applied to study mechanisms of Parkinson’s disease.

• Creating A Shigella Infection Model Using Organs-On-Chips

  Learn how researchers have utilized Organs-on-Chips technology to test the infectivity of Shigella through several experimental approaches.

• Modeling Complex Human Immune Response In A Novel Intestine-Chip

  Learn about immune cell recruitment, why it is important when researching inflammatory bowel disease (IBD) and other diseases, how Organ-Chips benefit IBD research, and more.

• Developing More Clinically Relevant Drug-Induced Thrombosis Models

  Learn how this Blood Vessel-Chip is capable of replicating drug side effects and mimicking the human circulatory system accurately, enhancing drug safety and efficacy in development.

• Boosting In Vitro Toxicology Testing With Organ-Chips

  Discover how Organ-Chips are enhancing preclinical testing, minimizing toxicity issues, and streamlining clinical trials for enhanced safety and efficiency.

• Advancing 3D Cell Culture Models For Clinical Relevance

  Concerns about in vitro relevance and animal study limits have advanced cell culture tech. Explore how Organ-Chips offer a refined approach to studying human physiology.

• Organ-Chips: A Promising Model For Human Emulation

  Organ-Chips offer more accurate assessments of safety and efficacy readouts compared to other cell and animal models used by academia, government, and pharmaceutical entities to study drug toxicity.

• Advances In Developing In Vitro Models Of Neurodegenerative Diseases

  Discover a more predictive in vitro model of the human brain that represents the next step in predictive biological models for neurodegenerative disease research.