ABOUT VERNAL BIOSCIENCES

mRNA-based therapies and vaccines are transforming medicine with rapid discovery and development, offering targeted, personalized treatments for a growing number of diseases. Yet, the journey from discovery to drug product remains complex, often requiring multiple vendors to manufacture your drug product. That’s where we come in.

We’re Vernal. The industry’s only seamless, end-to-end mRNA manufacturing platform that sustainably simplifies, de-risks, and accelerates your path from lead identification through candidate selection, IND and market approval. Our integrated technologies and systems enable the manufacturing of high purity drug substance, drug product, and intermediates using phase-appropriate control strategies.

With Vernal, you’ll have access to a team of technical specialists who exceed expectations. From manufacturing products with the highest in vivo potency and safety, to delivering consistent product quality across batches and scale up, we're all about setting the bar high. And our commitment doesn’t stop there. When challenges arise, we're right there with you, ready to find solutions to keep your project moving forward.

Whether your drug product is a cell therapy, gene therapy, or vaccine, start with Vernal—or seamlessly transfer your existing project to us. Together, we’ll accelerate the path to life-changing medicines.

SERVICES

 

 
DISCOVERY
Research

 
IND-ENABLING
Toxicology & DRF

 
CLINICAL
Phase I, II, III

 
COMMERCIAL
Market Approved

 
Mfg. Grade

 
Research Grade

 
PreCGMP

 
CGMP

Services

  • mRNA Design
  • Gene Synthesis
  • Research Cell Banking
  • Template Preparation
  • In Vitro Transcription
  • mRNA Purification
  • LNP Formulation
  • QC
  • Master Cell Banking
  • Release Testing
  • Stability Testing
  • mRNA Drug Substance Manufacturing
  • mRNA-LNP Drug Product Manufacturing
  • Sterile Fill-Finish

Validation

  • Process Development
  • Analytical Method Development
  • Analytical Method
  • Verification & Qualification
  • Process Development Established
  • Critical Process Parameters (CPPs) Established
  • Analytical Method Qualification
  • Process Performance Qualification
  • Continuous Improvement
  • Analytical Method Validation Completion

 

PRODUCTS

  • Catalog mRNA
  • Custom mRNA
  • Reporter Gene mRNA
  • Gene Editing & Regulation mRNA
  • Protein Replacement mRNA
  • Antigen mRNA
  • pDNA

MANUFACTURING

mRNA-LNP Center of Excellence • Vermont, USA

  • 21,000 ft2 facility
  • 3 Grade B CGMP cleanrooms
  • 3 Labs for Process & Analytical Method Development & Quality Control
  • 2 milligrams to 25 grams
  • ISO 9001 Compliant
  • CGMP Compliant: Full adherence to CFR, ICH, & Eudralex