Newsletter | November 9, 2026

11.09.26 -- Why You Should Measure Comparability Debt Before Ever Starting A Study

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Is Your Early-Stage CGT Supply Chain Ready for Late-Stage Scale Up?

As cell and gene therapies advance toward commercialization, scalable supply chains are critical to reaching patients reliably. On November 12, 2026 at 11 AM ET join Cell & Gene Live’s Erin Harris with Lineage Cell Therapeutics CEO Brian Culley and Allogene CTO Ben Beneski to explore cryopreservation, materials planning, inventory visibility, predictive analytics, chain-of-identity, and digital infrastructure. Register now for insights on building resilient, launch-ready operations.

FOCUS ON OUTSOURCING

Why You Should Measure Comparability Debt Before Ever Starting A Study

When analytical capability and process understanding fail to keep pace with a drug candidate, the technical uncertainty creates debt that's difficult to pay down.

Trends Shaping The Future Of Cell And Gene Therapy Manufacturing

Discover how automation and digitalization are transforming cell and gene therapy with scalable, decentralized manufacturing and smarter market navigation.

Inside The Bioprocessing Playbook For Scalable Biologics Production

Listen in as industry experts dive into the strategic role of cell culture media in driving scalable biologics manufacturing forward, highlighting practical insights for production.

The Adenovirus Revolution In Cancer Treatment

Adenoviruses are being reimagined as powerful tools for oncolytic cancer therapy, using their immunogenicity, tumor selectivity, and synergy with immunotherapy to drive new clinical progress.

Challenges And Opportunities With Novel AAV Capsids

Explore challenges and solutions in developing novel AAV capsids, focusing on manufacturing complexity, analytical testing, and regulatory considerations for advancing gene therapy effectiveness.

Targeted Gene Insertion Needs More Than One Tool

Targeted large gene insertion depends on matching the right mechanism to the biology. Engineered enzymes, recombinases, and retrotransposons help optimize efficiency and precision.

Efficient Plasmid Linearization: Type I & II Enzymes

Advanced plasmid linearization improves transfection efficiency and gene expression, delivering high-purity DNA with rapid turnaround, low endotoxin, and scalable processes for cell and gene therapy applications.

OUTSOURCING SOLUTIONS

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Automated Roller Bottle System Solution - Sanisure

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Services For Advancing mRNA-LNPs From Bench To Clinic - Cytiva

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Lentiviral Packaging & Producer Cell Lines For LVV Manufacturing - Minaris

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Need To Accelerate Your In Vivo CAR-T? You Need Lonza. - Lonza

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Cryopreservation Services For Leukapheresis-Derived Cell Therapies - Cryoport Systems

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