Why Programmable Logic-Gated Cell Therapies Matter

During this segment of Cell & Gene Live, "Building Smarter Cell Therapies with AI and Synthetic Biology," Senti Biosciences' Tim Lu, M.D., Ph.D., and Claire Aldridge, Ph.D., argued that next-wave CGTs must tackle indications where small molecules and biologics struggle by using multi-target, logic-gated designs to combine deep cancer killing with protection of healthy cells. They highlighted the need for better, more targeted delivery and dose control in gene therapies.