Article | January 12, 2026

Wetting Recommendations For Successful Pre- And Post-Use Filter Integrity Testing

Source: Cytiva
GettyImages-86809194-scientist-lab-filtration-equipment

Achieving accurate integrity testing starts with proper filter wetting. Explore critical considerations for wetting filters in both pre- and post-use scenarios, ensuring reliable performance and compliance. Learn when integrity testing should occur, how to select the right wetting fluid, and why complete wetting is essential for accurate results. Gain insight into tailored recommendations for hydrophobic and hydrophilic filters, including IPA/water wetting strategies, and offers step-by-step guidance for stainless steel and single-use systems. Delve into troubleshooting for integrity test failures and enhanced wetting techniques for challenging applications. Whether you’re working with volume-restricted systems or large-scale stainless steel setups, these best practices help streamline processes and reduce risk.

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