ViscoStar® On-Line Differential Viscometer
A highly sensitive, on-line differential viscometer used in conjunction with SEC-MALS-IV to determine the size and conformation of all types of biopolymers, synthetic polymers and even proteins and peptides.
Multiple Novel Technologies
The ViscoStar® incorporates multiple novel technologies to provide the highest sensitivity, stability and solvent compatibility of any available viscometer for GPC. Its ease-of-use and serviceability make it the perfect companion for Wyatt's DAWN® light scattering and Optilab® refractive index detectors.
Another path to polymer and protein characterization: SEC-MALS-IV
When coupled with size-exclusion chromatography and a concentration detector such as the Optilab, the ViscoStar derives the intrinsic viscosity (IV) of polymers. An inherently valuable physico-chemical property in itself, IV is best utilized together with molar mass information from multi-angle light scattering (SEC-MALS-IV) to derive the hydrodynamic radius, conformation, and branching ratio of a macromolecule in solution.
Key benefits of the ViscoStar
- High sensitivity, equivalent to 100 ng of 100 kDa polystyrene in THF at 1.0 mL/min injected onto a standard GPC column
- High dynamic range of over 135,000:1. The full measurement range corresponds to over 13 mg/mL of 100 kDa polystyrene in THF
- Extended solvent compatibility with all-316 stainless steel transducers
- Temperature range from 4 °C to 70 °C for polymers or proteins that require a range of temperatures
- Minimal band broadening thanks to fast pressure transducers
- Pump pulse suppression to below 4 Pa (hardware alone) or 1 Pa (hardware + software) without loss of chromatographic resolution
- Automated capillary bridge tuning with no moving parts, to guarantee a perfectly balanced bridge, every run
- Enhanced thermal stability with drift of <2.5 Pa/hour