Newsletter | November 10, 2025

11.10.25 -- Utilizing Adherent Cell Lines For Scalable Manufactuing Of Biologics, Vaccines, And Cell & Gene Therapies

AAV Production Using HEK293 In A Perfusion Process

A high-performing cell line, optimized reagents, and purpose-built technology are tested and proven in a perfusion process with data that supports scalability, productivity and higher quality drug products for gene therapy applications.

 

The Evolution Of AAV Production: Scaling Through Nature Instead Of Force

While the promise of AAV gene therapy is immense, traditional manufacturing has relied on “brute force” methods that are costly and inefficient. VintaBio is driving the evolution of AAV by harnessing a “scaling through nature” philosophy. Our purpose-built process creates a low-stress environment that mimics the natural, adherent state of the cells - allowing them to be more production.

 

Viral Vector Manufacturing: A Case For Adherent Cell Culture

Review how intensified adherent cell culture is challenging the dominance of suspension systems in viral vector production, offering improved productivity, reduced impurities, and scalable solutions that better align with the natural behavior of HEK 293 cells.

 

 

SOLUTIONS

VintaBio’s Approach To Viral Vector Manufacturing

VintaBio has cracked the code on adherent manufacturing, unlocking the full potential of anchorage-dependent cell lines for optimized vaccine, biotherepeutic, cell and gene therapy production.

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