Toxicity Studies

Aliri addresses the causes of toxicology through molecular histology, recognizing that about 50% of toxicology studies require investigations into the mechanisms of toxicity, particularly whether it is drug-induced or not. These investigations are essential for making informed Go/NoGo decisions during Lead Optimization programs or drug candidate selection.

By employing Multimaging™ technology (QMSI & microscopy), Aliri directly correlates the molecular distribution of targeted molecules, including both the parent drug and its metabolites, with histopathological and functional tissue changes. Utilizing statistical analysis and a proprietary metabolomics database, Aliri is able to detect and identify relevant molecular toxicity markers, providing critical insights into the safety profile of potential drug candidates.