Newsletter | March 20, 2024

03.20.24 -- The Future Of mRNA For Cancer Treatment

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Stem cells are the backbone of many allogeneic therapies and where they come from affects development and supply chain logistics, particularly cryopreservation. What temperatures are ideal to maintain product potency? How do you build a reliable cold chain? How do you work with existing infrastructure to allow for an “off-the-shelf” therapy? Don’t miss the next Cell & Gene Live digital event! Registration is free thanks to the support of Charter Medical and Bio-Techne.

FEATURED EDITORIAL

The Future Of mRNA For Cancer Treatment

As additional mRNA-based cancer immunotherapies vaccines enter clinical development, operational and supply chain challenges must be addressed to reduce turnaround times and COGS.

Supply Chain And Operational Challenges Facing mRNA

Explore some of the biggest supply chain challenges facing mRNA cancer therapeutics and what short-term solutions may exist, starting with Chain of Custody/Chain of Identity.

INDUSTRY INSIGHTS

7 Steps For Allogeneic Cell Therapy Success

To prepare allogeneic, or "donor-derived," CAR T cells for commercial scale, you must consider scaleup, aseptic processing, single-use systems, facility design, starting material, supply chain, and logistics.

The Medicines Of Tomorrow: A Primer On The Gene Editing Landscape

Learn about the distinction between gene therapy and gene editing, as well as the therapeutic potential of CRISPR treatments and the challenges associated with clinical trials and commercialization.

A Big Difference In Supply Chain Management Using Little's Law

Discover how leveraging Little’s Law to quantify metrics that otherwise would be causing confusion and process interruption can help to reduce wait times and deliver materials on time and within budget.

3 Benefits Of Partnering With A CDMO For CGT Manufacturing

By utilizing a CDMO's capabilities, pharmaceutical companies can focus on their core competencies and accelerate the development and delivery of life-saving therapies to patients.

Viral Vectors, Vaccines — A New Era Of Collaborative Design

Companies often turn to CDMOs to bring vector-based products to market, so it's important that they know how to assess a CDMO’s capabilities to help them achieve their goals.

Partnering At Every Stage: Providing Capable Capacity For Manufacturing

Finding a CDMO partner with the requisite expertise, materials, external supply chain, and capacity is key to maximizing a therapy’s chances of commercial success.

SOLUTIONS

Expertise, Experience, And Commitment Drives Results

Delivering LVV Material In An Accelerated Timeline

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