The Cell As The Delivery Vehicle
Dr. Murat Kalayoglu, CEO, Cartesian Therapeutics explains that Cartesian ensures that the cells it administers, and therefore the RNA therapeutics that is administers, meet all the specifications the company sets forth in advance. Part of those specifications ensures that there are a certain number of cells that are indeed capable of expressing the RNA into the relevant protein and at certain levels. He explains that they have solved the problem before ever infusing the RNA therapeutic directly into the body, and therefore, the class of therapies Cartesian develops are referred to as RNA cell therapy to distinguish them from conventional RNA therapies, where the RNA is either introduced directly or through nanoparticle.
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