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By Erin Harris, chief editor, Cell & Gene | Target selection is the defining challenge in CAR T therapy for solid tumors, shaping safety, efficacy, and the field’s path forward. Hear from clinical, translational, and scientific experts about the many perspectives to consider in target selection. | |
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| Engineering Rep-Cap Plasmids To Enhance AAV Potency | Poster | By Xiaojun Liu, Yeonji Kim, Chris Brown, and Jing Zhu, Recipharm Advanced Bio | Enhance AAV yield and quality through engineered Rep-Cap plasmids. This next-generation approach addresses core manufacturing hurdles to provide a more scalable solution for viral vector therapy. |
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| Streamline Viral Vector Clarification Using TFDF | Application Note | Repligen | Tangential Flow Depth Filtration (TFDF) intensifies virus production by streamlining the clarification process. Boost efficiency and yield for both LV and AAV manufacturing with this methodology. |
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| Preserving hMSC Phenotypes In Stirred-Tank Bioreactors | Application Note | Eppendorf SE | Reach metabolic stability and consistent growth in cell therapy applications. Research highlights successful hADSC expansion using microcarriers within scalable stirred-tank bioreactors. |
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| Combined Filtration For Mammalian Cell Clarification | Application Note | Cytiva | Consolidate cell clearance and sterile filtration into a single device. This approach simplifies the clarification of CHO-cells and other mammalian cultures for more efficient downstream work. |
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