Newsletter | September 30, 2025

09.30.25 -- STREAM Edition: Major Trends Impacting Allogeneic Cell Therapies For Oncology

Major Trends Impacting Allogeneic Cell Therapies For Oncology

Video | Cell & Gene

We kicked off this Cell & Gene Live, Unlocking the Future of Allogeneic Cell Therapy for Oncology, by discussing the major trends impacting allogeneic cell therapies for oncology.

 

Building A Commercial Model For CAR-T In Autoimmune Care

Video | Ori Biotech

In this episode of the Ori Spotlight Podcast, Warner Biddle, CEO of Kyverna Therapeutics, discusses how autologous CAR-T therapies can be delivered safely, efficiently, and at scale in autoimmune disease.

What Is Causing Limited Bioavailability?

Video | Aliri Bioanalysis

Discover how this label-free whole-body QMSI combined with plasma LC-MS/MS can help identify the root causes of limited bioavailability and guide smarter optimization strategies early in development.

Closing Ancillary Processes: The New Bottleneck In Cell And Gene Therapy

Video | Invetech

Peripheral systems remain open – introducing opportunities for failures. Learn about an approach that enables manufacturers to close and integrate both core and peripheral processes.

Manufacturing Life-Saving Gene Therapies

Video | Andelyn Biosciences

Capabilities span viral vector/vaccine process and analytical development, small to large scale adherent and suspension-based GMP drug substance manufacturing, and finished drug product services.

Reduce Batch Failure Risk With An Innovative Platform

Video | Cytiva

Enhance reliability in cell therapy manufacturing with an innovative platform. The closed system and automation reduce operator errors through smart monitoring, pre-checks, alarms, and batch reporting.

Overcoming Barriers To Unlock The Potential Of EV-Based Therapies

Video | Cell & Gene

In this segment of Cell & Gene Live, Redefining CGTs with Exosomes and EVs, Aegle Therapeutics’ Dr. Gloria Matthews identifies manufacturing scale-up as both the key progress point and the biggest challenge in translating extracellular vesicle (EV) therapies from lab to clinic. While regulatory comfort with cell therapies has helped pave the way, defining release assays and potency for EVs remains complex.