Stainless Steel Centrifuge for Cell and Gene Therapy Manufacturing: Powerfuge Pilot
Clean-in-Place / Sterilize-in-Place System
The Powerfuge Pilot is a high-power, batch liquid/solid separation system for bacteria, yeast, proteins and sub-micron particles. It is the smallest member of the Powerfuge family of centrifuges. The Powerfuge Pilot system is a two-phase centrifuge that meets cGMP requirements as well as chemical and pharmaceutical industry protocols.
- Bowl capacity: 1.1L
- Flow rates up to 60 L/hr for batches up to 100 L
- Dimensions ~ 35.6 cm wide x 56 cm deep x 56 cm high (14" x 22" x 22")
- Total weight ~ 115 kg (253 lbs)
- Fully scalable to larger automated P6, P12 and P18 models
- Drier solids, clearer centrates
How It Works
Using an innovative design that eliminates the need for bottles, the feed is introduced through a stationary pipe and accelerated to full rotational speed before entering the titanium-alloy bowl.
Benefits
Performance
With g forces up to 20,000 X g, the Powerfuge addresses even the most challenging separations.
Scalability
The Powerfuge family of products can be used for small process development volumes all the way to very large commercial manufacturing, allowing for seamless scale-up and scale-down.
Versatility
The Powerfuge is designed to serve the needs of a variety of markets.
Automation and General Specifications
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Allen-Bradley® or Siemens® PLC
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Allen-Bradley or Siemens HMI touchscreen 30.7 cm (12.1”)
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Maximum case pressure (for cooling) 6.9 bar (100 psi)
Utility Requirements
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Power configuration: Three phase voltage supply:
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US: 230V/60 Hz, 20 A
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Europe: 200V/50 Hz, 20 A
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Japan: 200V/60 Hz/50 Hz, 20 A
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Optional: Others as needed
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Pneumatic: Clean, dry air supply 6 bar (90 psi) at 1 SLPM
Process Wetted Parts Construction
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USP Class VI components
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316L Stainless Steel
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17-4 PH Stainless Steel
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Nitronic 60 Stainless Steel
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Platinum cured silicone hoses
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EPDM elastomers
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Ti-6Al-4V Titanium
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