Setting The Weld Standard: Validating Cleargreen®Pure Tubing For Closed-System Bioprocessing

As closed-system bioprocessing becomes the standard for cell and gene therapy manufacturing, the performance requirements placed on tubing continue to grow. Manufacturers need materials that support reliable sterile welding, maintain fluid purity, withstand sterilization processes, and align with evolving regulatory expectations. Traditional PVC tubing solutions often present challenges related to plasticizer content, gamma stability, and long-term process compatibility.

Recent comparative testing evaluated a next-generation PVC tubing formulation against widely used industry alternatives, examining critical performance factors including weld integrity, burst pressure, tensile strength, particulate generation, and hybrid weld compatibility. The findings demonstrate how modern tubing materials can deliver strong, consistent welds while maintaining low particulate levels and reliable mechanical performance after gamma irradiation. Equally important, compatibility with existing tubing platforms helps manufacturers modernize fluid management systems without major process changes.

For organizations advancing cell therapies, blood processing applications, and aseptic biologics manufacturing, understanding the relationship between tubing material selection and closed-system performance is essential. Explore the full white paper to see how evolving tubing technologies are helping support safer, cleaner, and more flexible bioprocessing operations.