Newsletter | May 22, 2026

05.22.26 -- Scaling RNA & LNP Manufacturing With Smarter Analytics

Intelligent mRNA Manufacturing Through Process Analytical Technologies

Learn how predictive models can monitor key CQAs, such as RNA concentration and nucleoside triphosphate consumption, and explore RBP and MIT’s vision for revolutionizing biomanufacturing.

Nucleic Acid-LNP Ultrafiltration And Diafiltration

Downstream filtration can make or break LNPs at scale. See how membrane format, loading, and shear affect recovery and stability — and how alternative TFF lowers scale‑up risk.

Laminar And Turbulent Mixing Techniques For LNP Formulations Scale Up

Explore the critical factors in scaling up lipid nanoparticle (LNP) formulation, comparing the advantages and limitations of both laminar (microfluidic) and turbulent (tee and jet) mixing technologies.

Screening T7 Polymerases To Optimize xRNA Yield And Quality

Discover how the evolution of T7 polymerase is optimizing in vitro transcription for RNA therapeutics. Learn to balance performance, cost, and supply to make smart choices for your xRNA manufacturing.

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