Newsletter | August 25, 2026

08.25.26 -- Reimagine Solid Tumor Immunotherapy With SRC-3-Edited Tregs

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Webinar: Evolving Lentiviral Vector Manufacturing with Stable Production

As in vivo lentiviral programs expand, manufacturers need scalable, reliable production platforms that deliver consistent quality. Join Asimov's Sybil Danby and Adam Carcella to explore next-generation LV manufacturing strategies, including producer and packaging cell lines, and learn how synthetic biology and computational modeling are improving titer, reducing variability, and accelerating development for both ex vivo and in vivo therapies. Click here to learn more.

FOCUS ON MANUFACTURING

Reimagining Solid Tumor Immunotherapy With SRC-3-Edited Tregs

CoRegen’s investigational autologous cell therapy, CRG-150, is designed to disrupt tumor-driven immune suppression by knocking out SRC-3 in Tregs, potentially exposing solid tumors to the patient’s own immune response without lymphodepletion.

Bridging The Gap: How Process Knowledge Moves From Lab To Launch

Learn how life sciences innovators use industrial data fabrics to eliminate manual tech transfer errors, bridge departmental silos, and accelerate time-to-market.

Maintain Sterility And Ease In CGT Development, Including Cryopreservation

Sterile connectors streamline cell and gene therapy processes while maintaining sterility. By withstanding extreme temperatures and cryoprotectants, they can ensure product viability during cryopreservation.

Data-Driven Bioprocess Development From Molecule To GMP Manufacturing

Optimize upstream bioprocessing from cell line development to commercial production. Leverage predictive data modeling and modular bioreactor systems for seamless scale-up.

Protecting Cellular Integrity In Automated Filling Systems

Automated fill-finish systems protect sensitive cell therapies using low-shear handling to maintain dose uniformity, cell viability, and process consistency across every batch.

Characterizing mRNA Using Ion-Pairing Reversed-Phase LC/MS

mRNA poly(A) tail analysis depends on targeted digestion, clean LC/MS conditions, and reliable deconvolution. See how RNase 4 digestion and optimized ion-pairing methods support reproducible results.

Why Freezing And Storage Should Not Be Designed Independently

Freezing and ultra-cold storage are often planned in isolation, but treating them as a single integrated system can reveal overlooked facility design opportunities.

Viral Vector Manufacturing Simplified: A Sponsor's Guide To Smarter Partnerships

Smarter viral vector manufacturing starts with early alignment, realistic scaling, and collaboration. Strategy and transparency reduce risk, control costs, and keep timelines on patients.

Cell Culture Media Mixing In A Benchtop Single-Use Mixer

Grasp how efficient powder-liquid mixing and sterile filtration preserve media integrity and support reproducibility in biopharmaceutical workflows, with promising scalability for larger-volume applications.

Unlock Viral Vector Yield And Efficiency With Upstream Intensification

Streamline viral vector manufacturing with perfusion technologies that reduce costs and improve scalability. Discover how a tangential flow depth filtration system enhances yield and quality.

Standardizing Starting Materials For Cell Therapy Production

From donor variability to collection site inconsistencies, cell and gene therapy faces raw material challenges. Ensuring stable, high-quality leukopaks is vital for effective treatments.

Expanding Pediatric Donor Pools Via Targeted T-Cell Depletion

Explore how T cell–depleted haplo-HSCT is expanding donor options for pediatric patients, with insights into clinical outcomes, immune recovery, and evolving strategies.

Overcoming Key Operational Bottlenecks In Virus Bank Manufacturing

Gain insights from two cases where clients overcame obstacles during virus bank manufacturing, from the technical transfer to the preparation of materials and documentation for the GMP campaign.

 

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Cell 2026 | 12-13 November, London, UK

Advanced therapy development moves fast, and the companies shaping it are the ones connecting science, scale and strategy in the same room. Cell 2026 is where that happens. Partner with us to reach 800+ senior pharma, biotech and R&D decision-makers through guaranteed 1:1 meetings, speaking slots, roundtables and tailored digital campaigns. Get in touch and we'll design a package around your objectives.

MANUFACTURING SOLUTIONS

Robotic Pharmaceutical Labeling Cell For Small Batch And Complex Shapes - HERMA

Versatile 10 L Single-Use Mixing System - Cytiva

Human Mesenchymal Stem/Stromal Cells Available In Three Formats - RoosterBio

A New GMP-Grade Endonuclease For VV Manufacturing - Roche CustomBiotech

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