Newsletter | July 23, 2025

07.23.25 -- Redefining CGT With Exosomes And EVs

SPONSOR

Webinar: Revolutionizing Cell Metabolism Monitoring: Inline, Real-Time Glucose and Lactate Analysis

This PHC webinar explores how real-time, inline monitoring of glucose and lactate using PHCbi's LiCellMo® technology can transform bioprocessing and cell therapy. Learn how continuous metabolic analysis improves cell viability, reduces variability, and accelerates decision-making—overcoming the delays and inconsistencies of traditional sampling methods to enhance product quality in biopharma, regenerative medicine, and academic research.

FOCUS ON TRANSLATIONAL RESEARCH

Redefining CGT With Exosomes And EVs

July’s Cell & Gene Live featured a comprehensive look at the scientific advances, clinical promise, manufacturing hurdles, and regulatory considerations shaping extracellular vesicle and exosome-based therapies. 

Development Of Sf-RVN Cell Line For Safer Sf9-Based Production

Explore the Sf-RVN cell line and EXCELL CD medium, offering a Sf-rhabdovirus-free alternative for BICS biologics production.

Immunohistochemistry In Precision Medicine: Biomarkers to Clinical Trial Assays

From preclinical validation to clinical implementation, immunohistochemistry (IHC) is essential in understanding target biology and ensuring drug safety and efficacy.

Enabling Transfer Of Raman Calibration Models Across Bioreactor Scales

Raman spectroscopy enables real-time monitoring and seamless calibration transfer from small to large bioreactors, boosting manufacturing scalability and efficiency.

A Duplex Assay For Quantification And Qualification Of AAV

Adeno-associated virus is a key gene therapy vector. Explore how digital PCR offers precise, standard-free quantification with improved consistency and inhibitor tolerance over traditional qPCR methods.

Viral Disinfectant Efficacy Studies: Key Guiding Factors And Design Elements

Viral Disinfectant Efficacy Studies validate cleaning protocols in pharma facilities, ensuring regulatory compliance, reducing contamination risk, and supporting safe disinfection with expert CRO guidance.

AI Unveils Tumor-Immune Landscape In Colorectal Adenocarcinoma

AI-powered multiplexed imaging and analysis explore the tumor-immune microenvironment in colorectal adenocarcinoma, identifying potential biomarkers for therapeutic insights.

Multicolor Flow Cytometry Panel Design

Watch video series on multicolor flow cytometry to master panel design fundamentals and discover strategies for streamlined, effective panel creation.

SPONSOR

Webinar: Accelerating Cell & Gene Therapy Scale-Up With An Advanced Manufacturing Platform

Discover how Oribiotech and ElevateBio are revolutionizing cell and gene therapy manufacturing with IRO —a next-gen platform delivering superior biological performance, real-time monitoring, and automated scalability. This webinar reveals how closed, efficient systems reduce costs and complexity while boosting consistency and quality from early development to commercialization. Learn how to scale smarter and faster in the evolving CGT landscape. Register here.

TRANSLATIONAL RESEARCH SOLUTIONS

Advancing Cell And Gene Therapy Development With Digital PCR - QIAGEN

TaqMan Assays To Support Your Oncology Research Breakthroughs - Applied Biosystems by Thermo Fisher Scientific, qPCR

Visualize Real-Time Changes In Cell Metabolism - PHC Corporation of North America

EVENTS

Advancing the Future of Cell & Gene Therapy

This 11-12 November, Cell 2025 unites 1,000+ leading experts across the CGT value chain to solve key challenges, from scalable bioprocessing and regulatory hurdles to accelerating development timelines.

 

Gain practical strategies across cell culture, therapy development, and CGT manufacturing, and hear from world-renowned leaders Bobby Gaspar (CEO, Orchard Therapeutics), Christof Von Kalle, (Director & BIH Chair, Research Clinic Luxemburg), and Dame Molly Stevens (University of Oxford). Register Now

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