Recombinant Human Transferrin: Optiferrin

Source: InVitria

In routine cell culture, transferrin is customarily supplied as a natural component of fetal bovine serum (FBS). The growing use of serum-free, chemically defined media in the culture of cells destined for downstream clinical therapeutic applications, however, necessitates use of a purified, recombinant form of this essential component.

InVitria’s recombinant human transferrin, Optiferrin, is completely free of animal and human components and is produced in a scalable, non-mammalian expression system. It is fully human in primary sequence, is ⍺-glycosylated during expression in the host, and shares secondary and higher-order structural equivalence with naturally occurring human holo-transferrin. Its functional performance in cell culture is equivalent to human holo-transferrin in terms of reversible iron binding, transferrin-receptor binding, and promoting cell growth and productivity.

Optiferrin is naturally free of prion agents and carries a far lower potential risk of contamination with other human or mammalian adventitious agents compared to serum-derived components and recombinant proteins produced in other systems. Its purity makes it ideal for demanding research and commercial applications.

Need More Information? Just Ask.

Click the button below to directly contact the supplier. Use it to:

  • Ask a question.
  • Request more detailed information or literature.
  • Discuss your current project/application.
  • Request a quote.
  • Locate a distributor in your area.
  • Schedule a demo.
Request Information