Quality Control Solutions For Cell And Gene Therapy

Droplet Digital PCR (ddPCR) provides highly precise and absolute quantifications of nucleic acids by counting nucleic acid molecules encapsulated in discrete water-in-oil droplets. Droplets are formed in a water-oil emulsion to form the partitions that separate the template DNA molecules. The droplets serve essentially the same function as individual test tubes or wells in a plate in which the PCR reaction takes place, albeit in a much smaller format. The massive sample partitioning is a key aspect of the ddPCR technique.

The Droplet Digital PCR System partitions nucleic acid samples into thousands of nanoliter-sized droplets, and PCR amplification is carried out within each droplet. This technique has a smaller sample requirement than other commercially available digital PCR systems, reducing cost and preserving precious samples. Learn more about how Bio-Rad's ddPCR Systems and Software can be used in Cell and Gene therapies and how they meet the needs of GMP manufacturing and QC environments.