Application Note

Primary Clarification Of CHO Cells With Single-Use Centrifuge Technology


<p>Until the advent of single-use centrifugation, there was little choice for the primary clarification step and technology within single-use bioprocesses. This changed with the arrival of the single-use centrifuge. Manufacturers face several challenges within the production of monoclonal antibodies, and require a technology that reduces filtration footprint while maintaining a low-shear environment for cells.</p> <p>The UniFuge Pilot&reg; single-use cell harvesting system is specifically designed for primary clarification of mammalian cell cultures (such as CHO cells) and harvesting. This data presents a cell culture clarification process using the UniFuge Pilot and how it addresses the issues manufacturers face.</p>


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