Overcoming Immunogenicity and Manufacturing Challenges in Adenoviral Gene Therapy
Source: Cell & Gene
In this segment of Cell & Gene Live, Advancing Gene Delivery: LNPs, Adenovirus, Lentivirus, And More, Francesca Barone, M.D., Ph.D., CSO at Candel Therapeutics and Karen Kozarsky, Ph.D., President of Vector BioPartners explore strategies to overcome immunogenicity and toxicity in adenoviral vectors, discussing the benefits of intratumoral delivery, serotype switching, and viral gene deletions.
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