Overcoming Cell Therapy Manufacturing Challenges With Closed, Modular And Automated Solutions

Top manufacturing challenges and solutions across the autologous T-cell therapy workflow

The typical workflow is a very complex and labor-intensive process with multiple stages where contamination and errors can greatly affect the desired outcome.

1. Several open processes where contamination can occur
2. Process complexity utilizes a multitude of products
3. Labor-intensive multi-step process increases error potential
4. Instruments lack flexibility to facilitate different process steps
5. Lack of in-line monitoring throughout workflow
6. QC (release testing) is time consuming and expensive: >30% of total cost
7. Zero failure tolerance

This infographic provides an overview of considerations as you scale your manufacturing process for commercial settings and how to put solutions into practice.

This infographic was originally produced by RegMedNet, in partnership with Thermo Fischer Scientific.