Article | October 14, 2025

Optimize, Automate, And Scale Closed-System MSC Expansion

FUJIFILM Biosciences – closed system

As Mesenchymal Stem Cells (MSCs) become central to regenerative medicines and cell therapies, manufacturers must find ways to efficiently automate their production to meet market demand. Achieving target cell quantity and quality at an economical cost relies on moving to closed-system manufacturing that reduces risk and variability.

Unlike many immunotherapies, MSC applications require both basal media and a full complement of supplement growth factors, making a comprehensive, ready-to-use closed system critical. A novel dual-component kit is now available that streamlines the process for hollow-fiber platforms like Quantum Flex. This approach provides a complete, xeno-free, serum-free solution in a simple, bag-to-bioreactor construction. It is designed to support high expansion rates and viability, offer greater control by minimizing manual handling, and ensure a seamless, simple scale-up from research to commercial manufacturing.

Explore the full article to understand how a unified, closed-system approach can optimize, automate, and scale your MSC expansion.

access the Article!

Get unlimited access to:

Trend and Thought Leadership Articles
Case Studies & White Papers
Extensive Product Database
Members-Only Premium Content
Welcome Back! Please Log In to Continue. X

Enter your credentials below to log in. Not yet a member of Cell & Gene? Subscribe today.

Subscribe to Cell & Gene X

Please enter your email address and create a password to access the full content, Or log in to your account to continue.

or

Subscribe to Cell & Gene