Oligonucleotide Discovery And Development

Developing therapeutic oligonucleotides requires a specialized understanding of their unique biological, chemical, and physical characteristics that set them apart from traditional drug modalities. From discovery to commercial-stage analytical testing, a tailored approach is critical to avoid costly delays and overcome formulation and delivery challenges. This is where expert contract R&D support becomes essential.

With extensive experience across a wide range of oligonucleotide formats—including ASOs, siRNAs, conjugates, PMOs, and more—dedicated scientists provide technical solutions that keep your program moving forward. Services span from analytical method development and validation to GMP release and stability testing. Cutting-edge tools, such as LC-MS, dPCR, and next-generation sequencing, further support discovery and bioanalytical efforts across diverse platforms like LNPs, VLPs, and high-concentration formulations.

Whether you're optimizing delivery, refining analytical methods, or advancing a therapeutic candidate toward IND or commercialization, tailored scientific and technical support can accelerate success. Discover how custom oligonucleotide solutions can advance your program.