Newsletter | June 20, 2025

06.20.25 -- Navigating CGT Biotech's Financial Headwinds And The Path Forward

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Explore the evolving role of exosomes and extracellular vesicles (EVs) at the next Cell & Gene Live. Chief Editor Erin Harris moderates a discussion with Capricor’s Linda Marbán and Aegle’s Dr. Gloria Matthews on clinical and commercial advances, including applications in rare and cardiovascular diseases. Gain insights into the future of exosome-based therapies from leaders driving innovation across R&D, manufacturing, and commercialization.

FOCUS ON SUPPLY CHAIN

Navigating CGT Biotech's Financial Headwinds And The Path Forward

Dr. Ali Pashazadeh, Founder of Treehill Partners shares how CGT companies can navigate today’s biotech downturn by embracing integrated strategies, disciplined capital use, and bold leadership willing to rethink traditional models across innovation, manufacturing, and commercialization.

How Controlled Freezing Becomes Reality

Controlling the freezing behavior of bulk drug substance is the ultimate goal in biopharma manufacturing. This study demonstrates the impact of ice front growth speed on scalability of freezing protein solutions.

SUPPLY CHAIN SOLUTIONS

GORE STA-PURE Flexible Freeze Container User Guidelines - W.L. Gore & Associates

FOCUS ON CLINICAL TRIALS

Everything To Know About Long-Term Data Collection For Cell And Gene Therapy Trials In The EU

Discover how to secure uninterrupted access to long-term trial data for CAR-T therapies by participating in the European Society for Blood and Marrow Transplantation (EBMT) CAR-T Data Collection Initiative. 

Small Cell Lung Cancer: Global Clinical Trial Landscape (2025)

Historically dominated by chemotherapy and radiation, the treatment paradigm for small cell lung cancer (SCLC) is evolving in response to limited survival benefits and high relapse rates.

High Density, Low Availability: Rethinking Ophthalmic Trial Readiness

The adoption of mobile ophthalmic solutions and collaboration with specialized vendors is recommended to ensure trial consistency and reach underserved regions.

The Evolving Landscape Of Radiopharmaceuticals In Oncology Research

From selecting appropriate targeting molecules to optimizing dosing strategies and managing off-target effects, radiopharmaceutical development demands a tailored and strategic clinical approach.

A High-Touch, Patient-Centered Approach For Advancing Rare Disease Trials

On your journey to developing and executing a successful rare disease trial, it is critical to focus on patient experience and accessibility from the earliest stages of trial design.

A Smartphone-Based Biomarker For Unipolar Depression Severity

The study investigates the potential of using smartphones and wearables to create objective biomarkers for mood disorders, specifically focusing on unipolar depression.

Driving Diversification And Reach With Tech In Community DCTs

Learn how technology, when used correctly, can accelerate trial timelines and drive patient diversification in community-based decentralized clinical trials (DCTs).

Why Academic Researchers Rely On A Clinical Trial Recruitment Solution

Explore a solution created to meet the clinical trial patient recruitment needs of academic research organizations that is particularly adapt at engaging minorities and under-represented groups.

Initial IRB Submission: 7 Fundamentals Of Success

The initial IRB submission process can involve common challenges. To help you overcome these obstacles, discover seven fundamentals you should know about a successful initial IRB submission.

CLINICAL TRIALS SOLUTIONS

Lock Into Your Go-To Data Strategy - Biorasi

Implementing Complex Ordering Workflows Has Never Been Easier - InspiroGene

Commercial Alerts: Now Available With EHR, Claims And Prescription Data - Quest Diagnostics

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