Multiplex Adventitious Virus Detection With QIAcuity dPCR For Viral Safety Testing

Ensuring viral safety is central to biologics manufacturing, and sensitive methods are essential for detecting potential human viral contaminants. Explore how multiplex digital PCR for biosafety and QC labs streamlines targeted adventitious virus testing by enabling rapid, precise detection of multiple viral agents in a single workflow. A curated 13‑virus panel, divided in RNA and DNA multiplex assays, demonstrates how focused, high‑multiplex assays can maintain accuracy, specificity, and clear signal separation even when consolidating targets. Validation data show strong concordance between singleplex and multiplex formats, underscoring reliability for QC and biosafety applications. Readers gain a clear view of how dPCR complements broader approaches like NGS and fits within risk‑based frameworks such as ICH Q5A(R2).

Access the full application note to see performance data, panel composition, and guidance for tailoring viral detection strategies to unique manufacturing risks.