Mixing Modes In IRO® For CAR-T Manufacturing

The IRO® Bioreactor offers three distinct mixing modes—Static, Rock, and Compression Mixing—each designed for different phases and media volumes within a standard CAR-T manufacturing workflow. Static mixing, comparable to a T-flask, is ideal for small initial volumes, while Rock Mixing provides gentle convective mixing for moderate volumes during activation and transduction. For larger volumes and higher cell densities, Compression Mixing offers superior potential for mixing and oxygen mass transfer.

Understand how these flexible operating parameters, including agitation rate, rock angle, and stroke length, can be fine-tuned to optimize your process. Explore the full application note for detailed insights into these powerful mixing capabilities