miniDAWN® Multi-Angle Light Scattering For Absolute Macromolecular Analysis

Source: Wyatt Technology
Wyatt miniDAWN

The best in basic multi-angle light scattering for absolute macromolecular analysis

Molar Mass

The miniDAWN® determines absolute molar mass and size to characterize proteins, peptides, small polymers and nanoparticles in solution. Coupled to size exclusion chromatography (SEC or GPC), it eliminates the uncertainty and hassle of column calibration, for true confidence in macromolecular characterization.

Superb Sensitivity

The miniDAWN not only offers superb sensitivity—it further enhances productivity thanks to greatly enhanced field serviceability and easy data analysis with One-Click Mw.

Compatible with ASTRA®

The miniDAWN is accompanied by ASTRA, the most versatile software package available for analysis of online multi-angle and dynamic light scattering. ASTRA and the miniDAWN incorporate advanced ease-of-use features that help guarantee excellent measurements with a single click

Molar mass, absolutely

Wyatt's miniDAWN is most often used in conjunction with size exclusion chromatography (SEC-MALS) or field-flow fractionation (FFF-MALS) to determine distributions of molecular weight, size and composition. No need to make assumptions about molecular conformation or ideal column interactions.


  • Proteins, small peptides and oligonucleotides
  • Synthetic and natural polymers
  • Nanoparticles, virus-like particles and vesicles

Measurement Range:

  • MW from 200 Da to 10 MDa
  • rg from 10 to 50 nm, up to 150 nm with shape-specific models
  • sensitivity down to 25 ng of 100 kDa polystyrene in THF, injected on a standard GPC column

The miniDAWN's performance is exceeded only by the DAWN® which covers a wider range of size and molecular weight, with even better sensitivity and additional optional modules.