Newsletter | January 20, 2025

01.20.25 -- Lessons In Automation With Roswell Park Comprehensive Cancer Center's Christopher Choi, Ph.D.

FOCUS ON OUTSOURCING

Lessons In Automation With Roswell Park Comprehensive Cancer Center's Christopher Choi, Ph.D.

On Cell & Gene: The Podcast, Erin Harris interviews Dr. Christopher Choi of Roswell Park Comprehensive Cancer Center about the upcoming cell and gene therapy hub in Buffalo, NY, set to open in 2025. They delve into the transformative role of automation and digital technologies in CGT manufacturing. Dr. Choi also shares practical advice for emerging CGT biotechs on navigating manufacturing challenges during early product development.

Navigating Complex Testing For Viral Vector-Based Gene Therapies

To ensure the success of gene therapy, learn why it is crucial to partner with a CRO that can navigate the challenges of viral vector development and testing.

The Cryoport Elite Shipping System

The Cryoport Elite shipping system sets a new standard for the transport of sensitive biopharmaceuticals. Explore its pioneering features and industry impact with Mike Dybicz, SVP & CPDO at Cryoport Systems.

Analytical Comparability Of Five Alternative AAV9 Downstream Processes

Explore how two-column AAV processes can enhance yield and potency while maintaining high-quality standards in the production of gene therapy products.

The Promise Of Augmented Reality In Cell Therapy Manufacturing

Augmented reality enables drug sponsors to provide remote assistance and direction to their manufacturing team during tech transfer and improving the effectiveness of manufacturing processes.

cGMP-Ready Clonal HEK293 Cell Line For Adenoviral Vector Production

See how this advanced SKPT-HEK293 4G9 was able to provide a robust, CGMP-ready solution for efficient viral vector production.

The Benefits Of Streamlining And Standardizing Plasmid DNA

The need for greater volumes of high-quality raw materials like plasmid DNA in the cell and gene therapy space has made pDNA standardization integral to streamlining the development process.

Novel Engineered Plasmids And HEK293 Cell Line Improves Productivity

Low AAV productivity and lack of platform processes continue to be key challenges driving AAV production cost up. Explore a robust and scalable suspension manufacturing platform for AAV production.

Optimization Of In Vitro Transcription For mRNA Production

Optimize your mRNA production with an advanced IVT process, enhancing scalability, purity, and expression activity for clinically relevant RNA therapeutics.

The Benefits Of Allogeneic Cell Therapy

Allogeneic therapies leverage donor cells to ensure optimal starting material and ensure patients can receive treatment without delays, ultimately helping to improve safety and expand patient access.

OUTSOURCING SOLUTIONS

Enhance DMC Services By Harnessing Biostatistics Expertise - Veristat, Inc.

Capacity Update October 2024: Cell & Gene Therapy - WuXi Advanced Therapies

Advancing Innovative Plasmid DNA Manufacturing Solutions For CGT - Aldevron

Manufacturing GTP And GMP - Comprehensive Cell Solutions, A Business Unit of NYBC Enterprises

RNA Therapies - ReciBioPharm

Helping Cell Therapy Innovators Bring Treatments To Market - Kincell Bio

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