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Transfection methods are used for a range of applications. This technical guide provides information on the most common methods of gene delivery and compares them to Nucleofection. Delve into their advantages, disadvantages, and ideal applications.
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Amongst the vector free technologies, electroporation is considered the gold standard. Explore an improved cartridge for the electroporation of complex cargos into large volumes of T cells. Discover how to achieve reliable, robust, and efficient delivery of clinically relevant cargos.
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Gamma delta T cells are well suited for a wide variety of treatments due to reduced risk of graft-versus-host disease, enhancing their overall safety profile. Review two methods for clinical scale expansion of gamma delta T cells: zoledronic acid activation and anti-CD3/CD28 activation.
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This paper underscores the 4D-Nucleofector® LV Unit as a pivotal tool for translating genetic modification technologies into scalable, safe, and effective therapeutic solutions, fostering advancements across the CGT landscape. Gain insights into researchers' work and achievements.
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To address multiple pain points, complementary technologies were combined to enable non-viral gene delivery for cell immunotherapy manufacturing in a functionally-closed, automated workflow. The study objective was to demonstrate their ability to modify primary T cells.
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