Application Note

Improve Viral Stability For Vaccines And Gene Therapies

Source: InVitria
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Exbumin® is a recombinant human serum albumin that is manufactured using good manufacturing practices at an ISO9001:2015 certified facility in Kansas, USA. It is blood-free and has been used in hundreds of thousands of injections. Exbumin is one of the few excipients available to improve viral stability for vaccines and gene therapies. Exbumin is also used to maintain tissue viability during cryo-preservation or storage. In addition, Exbumin is used to stabilize cells and tissues used in cell therapy and regenerative medicine applications. Exbumin has been approved for use as an excipient in injectable therapeutics by regulatory agencies.

Workflow Summary

Weigh Exbumin (lyophilized powder) and determine final total volume of the solution. Add 70% of the final volume of DPBS, PBS, or basal media. Let sit for 12 hours at 4°C. QS volume to account for volume increase from powder. Sterile filter and store at 2-8°C or freeze at-20°C for long term storage.

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