Newsletter | November 4, 2024

11.04.24 -- How To Promote Batch-To-Batch Consistency In CAR-T Therapies

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WuXi Advanced Therapies has recently published a 20+ page eBook on How-To Master Tech Transfer: Strategies To Sidestep Common Pitfalls. Download today for practice advice and insights including 8 typical stumbling blocks to avoid, 7 unique challenges for ATMPs and more!

FOCUS ON OUTSOURCING

How To Promote Batch-To-Batch Consistency In CAR-T Therapies

Patient immune cells and varied raw materials introduce inherent biological variability into CAR-T therapy manufacturing, making it a constant balancing act of adjusting processes and technology to minimize batch-to-batch variability.

Realizing The Potential Of Intensified Scalable Adherent Cell Culture

Review the importance of alternative approaches to viral vector production and the benefits of intensified adherent cell culture for improving efficiency, reducing costs, and accelerating development.

Upstream Optimization Paves The Way For Full Capsids In AAV6

Because clinical applications for AAV are increasing rapidly, there is a high demand for further increasing yields as well as product quality, particularly for a higher percentage of full capsids in the final product.

The Role Of Platform Processes In Cell Therapy

Learn how the streamlined processes and reduced complexity enabled by a platform approach can lead to scalable manufacturing, rapid delivery, and expanded patient access for cell therapies.

Revolutionizing Gene Therapy Manufacturing With Next-Gen rAAV Production

See how a next-generation rAAV production platform delivers high yields and superior product quality across various serotypes and genome lengths through innovative process optimization.

Accelerated Adventitious Virus Testing In Viral Vector Vaccines

Implementing NGS technology for adventitious virus testing in viral vector vaccine development and manufacturing is crucial for ensuring safety. Gain insights for an optimized sequencing method.

Identifying Sustainable Pathways Toward Oligonucleotide Therapeutics

Advance sustainable oligonucleotide manufacturing by adopting innovative solutions that reduce environmental impact while addressing the growing demand for therapeutic oligonucleotides.

Leveraging Platforms To Create Vaccines At Pandemic Speed

In this presentation, speakers share how the University of Queensland rapidly developed a vaccine candidate for COVID-19 and the role GS Xceed system played in the project.

A Continuous Electroporation System For Viral Gene Therapy

Explore the development work involved for the individual technologies that make up an innovative and scalable, chemical-free continuous viral vector production platform.

A Feeder-Free Platform For Generating Mature Natural Killer Cells

NK cells represent a promising avenue for immunotherapy. Examine the advantages of NK cells in cellular immunotherapy and the importance of developing efficient activation and expansion platforms.

Enabling Novel CRISPR-Cas9 Delivery: Supporting Innovative Genomics

A CRISPR research institute needed a custom, ultra-pure nuclease with low endotoxins—see how Aldevron's expertise lowered immune responses compared to AAV serotype 9.

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Webinar: Harnessing mRNA Quality Insights: Essential Techniques for Rapid Drug Development

In this webinar, attendees will learn advanced analytical techniques, such as Sanger sequencing and mass spectrometry, to optimize formulations and identify issues early in development. By mastering these methods, drug developers can enhance product quality and accelerate the path to successful mRNA-based therapeutics. Join us to unlock insights that drive clinical success and innovation in medicine. Click here to learn more.

OUTSOURCING SOLUTIONS

Seamless, End-To-End Cell And Gene Therapy CDMO - GC Cell

The Andelyn Difference - Andelyn Biosciences

Cell Line Characterization Testing Package - WuXi Advanced Therapies

Help Bring Your Breakthrough Cancer Treatments To Market Faster - Parexel International

Comprehensive CGT And Nucleic Acids Analytical Capabilities - SK pharmteco

UpTempo AAV Platform Process - Catalent

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