Newsletter | April 24, 2025

04.24.25 -- How Cynata Therapeutics Is Unlocking The Power Of iPSCs To Transform Regenerative Medicine

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Setting the Standard in CGT: Perspectives on Performance, Scalability, and Regulatory Compliance

Explore the evolving landscape of cell and gene therapy with insights from key opinion leaders. This white paper addresses challenges in process development and manufacturing across different modalities. Discover how end-to-end solutions can accelerate commercialization by prioritizing performance and scalability while simplifying the path to regulatory approvals. Download it to learn innovative strategies that are setting the standard in cell and gene therapy.

FOCUS ON MANUFACTURING

How Cynata Therapeutics Is Unlocking The Power Of iPSCs To Transform Regenerative Medicine

Cynata Therapeutics is pioneering a scalable, iPSC-based platform to produce consistent, high-quality MSCs that are showing strong clinical promise across multiple indications, including GvHD, diabetic foot ulcers, and osteoarthritis.

The Dynamic Role Of Processing Speed In Cell Separation Outcomes

How does the processing speed of cell separation methods impact product quality, process efficiency, and overall economics?

Introduction To Tangential Flow Filtration

Learn about tangential flow filtration (TFF), typical TFF system configurations, ultrafiltration fundamentals, applications, system selection considerations, and more.

Utilizing Quantitative PCR For The Assessment Of AAV Shedding

Explore AAV shedding assessment using qPCR, featuring experts discussing assay development, monitoring challenges, and ensuring safety in clinical studies.

Analytics: A Referee For Between MSC-EVs' Nature And Nurture

Like a referee in a contest, advanced analytical methods are essential to mediate the push and pull of different factors influencing therapeutic efficacy.

A Multiplexed High Throughput Method To Evaluate Novel Nuclease Activity

Efficiently evaluating the activity of novel nucleases with unique properties requires a high-throughput, multiplexed approach that enables direct comparison across multiple genomic targets.

Co-Precipitation Of Metal Carbonate Templated Protein Microparticles

Explore the automated production of protein microparticles using an innovative method that offers a standardized and scalable solution for co-precipitation in biopolymer particle fabrication.

The Modular Advantage: Stick Built Vs. Modular

There are three major options when building a pharmaceutical grade cleanroom on your existing site — stick built, modular, or podular. Here, modular installation and stick built construction are compared.

Optimizing Stem Cell Culture Conditions

Discover how you can revolutionize your stem cell research with a stable, plant-based growth factor that simplifies culture maintenance and boosts cell health.

Linear Scale-Up Of hiPSC Cell Lines Using Vertical-Wheel Bioreactors

Explore how innovative bioreactor technology enables consistent and efficient scale-up of human induced pluripotent stem cells (hiPSCs) from 100ml to 3L, ensuring optimal cell yield and quality.

The Evolution Of Nucleotide Production

From harsh chemicals to gentle enzymes: Explore the groundbreaking shift in nucleotide synthesis, making drug manufacturing cleaner, greener, and more efficient.

MANUFACTURING SOLUTIONS

Flex Mixing System - Entegris, Inc.

Prefilled Syringe Plungers - West Pharmaceutical Services, Inc.

Make The Most Of Your Measurements - Refeyn

Cleaning And Disinfectant Bucket System For Manufacturing - Contec, Inc.

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