09.05.24 -- Great siRNA Science Or Savvy Business Acumen? You Need Both

By working with a single supplier that can handle the entire manufacturing value chain, companies can reduce risk, improve flexibility, and accelerate their time to market.

Augmented reality allows drug sponsors to remotely assist their manufacturing team during tech transfer, cutting costs, speeding timelines, and enhancing process effectiveness.

Explore how the bYlok® bispecific pairing technology can be used to solve heavy-light chain mispairing in bispecific antibodies and how it compares with alternative scaffolds.

Learn how an adapted cell line can reduce costs and improve scalability in the production of lentiviral vectors for CGTs and examine its potential to produce GMP-grade lentiviral vectors.

While clinical efficacy is the critical benchmark for any drug program, ensuring manufacturability is also vital. An experienced CDMO can help you establish efficient and cost-effective production strategies.

Here, we outline how the upstream and downstream workflows of the VirusExpress® platform for lentiviral vectors were optimized through the use of design of experiments and supplementary studies.

Review a description of research grade and process development productions of rAAV6, both based on transient transfection of serum-free cells grown in suspension.

Consider a HEK293-derived animal component-free suspension cell line as the foundation of an up to 2000-liter scalable and robust platform process that increases the speed of AAV manufacturing.