Newsletter | March 16, 2026

03.16.26 -- From Discovery To AAV Production: Tools To Accelerate Gene Therapy

Primary Normal Human Cells, Media: In Vivo Relevance. In Vitro Results.

Bridge the gap between in vitro research and human physiology by utilizing high-purity primary cells. Accessing diverse cell types and optimized media ensures your gene therapy discovery remains biologically relevant and reproducible.

 

Facing Challenges In Gene Therapy Development

In this two-minute preview, we take a high-level look at the entire gene therapy development journey — from discovery and preclinical research to process development, manufacturing, regulatory engagement, and clinical trials. Along the way, we highlight the critical bottlenecks that often stand between promising science and successful patient delivery.

 

Flexible Cell Culture Media For High Titer Production Of AAV In HEK 293

Recent data shows that using a chemically defined, animal-origin-free media system can significantly improve AAV production across serotypes such as AAV2, AAV8, and AAV9. Optimizing viral titer and full capsid yield requires systematic process development, with cell culture medium selection serving as a foundational factor.

 

SOLUTIONS

Improve Viral Titers In Your AAV Program

Achieve superior AAV production yields in suspension HEK293 cells. This chemically-defined media system offers flexibility, robust growth, and can boost viral titers up to 3x. It's ready for GMP manufacturing.

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