Evaluating Novel Whole Blood Preservation Methods As Alternatives To PBMC

In this webinar, Dr. TJ Beadnell and Dr. Virginia Litwin present findings from a feasibility study exploring alternative methods for whole blood preservation in immunophenotyping for clinical trials, with a focus on improving specimen stability and overcoming logistical challenges in global studies. They discuss common issues associated with PBMC isolation and sample handling, and evaluate preservation products such as Smart Tubes, Cytodelics, and CryoStor® CS10.

The webinar also compares the performance of preserved whole blood with cryopreserved PBMCs and shares practical insights from using Eurofins Viracor BioPharma’s 26-color Spectral Panel-1 for flow cytometry immunophenotyping. Additionally, key considerations such as marker resolution, antibody titration, and study-specific context are highlighted, along with how alternative collection methods can streamline logistics and increase accessibility for study sites.