Newsletter | September 17, 2025

09.17.25 -- Developing Interleukin-2 For Cell Therapies: Key Considerations

SPONSOR

Webinar: Advancing Non-Viral Gene Editing: CellShot® PFEP Technology and Proliva™ for Enhanced Post-Electroporation Performance

Join FEMTOBIOMED's webinar to discover how the CellShot® platform is transforming non-viral gene delivery with PFEP™ electroporation and Proliva™ technology. See real-world data proving higher viability, proliferation, and efficiency in CRISPR and TALEN workflows. Gain actionable insights to optimize research and GMP manufacturing. Don't miss this opportunity to overcome gene-editing bottlenecks and accelerate your programs. Click here to learn more.

FOCUS ON TRANSLATIONAL RESEARCH

Developing Interleukin-2 For Cell Therapies: Key Considerations

By promoting cell expansion, survival, and functionality, interleukins help optimize therapeutic outcomes in cancer immunotherapy and regenerative medicine. Let’s look closer and compare ex vivo and in vivo approaches.

Thermal Stability Of Phosphoramidites In Oligonucleotide Synthesis

Crucial for efficacy, thermal stability in RNA/DNA therapies hinges on phosphoramidites: A study highlights key factors for process safety and quality in oligonucleotide development.

How To Evaluate And Compare Real-Time PCR Reactions

Learn about the key factors that influence qPCR reaction performance and provides guidelines for evaluating and comparing reactions run under varying conditions to ensure reliable data interpretation.

Oligonucleotides: Where We Are And Where We Would Like To Go

Explore the current knowledge and future directions of the bioanalysis of oligonucleotides. Review the pros and cons of various analytical platforms, methods of extraction, and approaches for these molecules.

Mitigate Gene Editing Program Risk Through Off-Target Safety Profiling

A critical challenge for therapeutic programs using CRISPR is managing the risk of off-target effects. Learn how to strengthen the safety of your therapeutic programs with comprehensive assessments.

Expanding Translational Research Concepts

The biopharma industry leverages Genedata Profiler to integrate, curate, and analyze diverse R&D data, enabling collaborative, compliant, and AI-driven translational research to optimize drug development.

Navigating Next-Generation Quality Control Strategies For AAV Testing

AAV-based gene therapies, while promising, require rigorous quality control through advanced methodologies to ensure safety, efficacy, and regulatory compliance.

SPONSOR

Webinar: Evolving Gene Editing for Rare Disease Drug Development

Danaher is partnering with leading academic and clinical research institutes focused on the development of a novel platform approach to gene editing aimed at accelerating the delivery of therapies and creating economies of scale to treat ultra-orphan conditions. We will explore how to create scalable models for efficient manufacturing and broader patient access and formulate regulatory and clinical strategies to address rare disease challenges. Learn more.

TRANSLATIONAL RESEARCH SOLUTIONS

Multicolor Panel Solutions For Flow Cytometry - BD Biosciences

Ready-To-Use Exosomes That Streamline R&D - RoosterBio

EVENTS

Advancing the Future of Cell & Gene Therapy

This 11-12 November, Cell 2025 unites 1,000+ leading experts across the CGT value chain to solve key challenges, from scalable bioprocessing and regulatory hurdles to accelerating development timelines.

 

Gain practical strategies across cell culture, therapy development, and CGT manufacturing, and hear from world-renowned leaders Bobby Gaspar (CEO, Orchard Therapeutics), Christof Von Kalle, (Director & BIH Chair, Research Clinic Luxemburg), and Dame Molly Stevens (University of Oxford). Register Now

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