Residual host cell DNA (HCD) that carries over during the process of manufacturing therapeutic proteins and vaccines poses safety concerns and must not exceed levels established by regulatory agencies such as the U.S. Food and Drug Administration and the World Health Organization. Bio-Rad’s ddPCR Residual DNA Quantification Kits are ideal for highly precise quantification of HCD in complex bioprocess intermediates. The kits contain an optimized ddPCR CHO or E. coli Residual Quantification Assay and ddPCR Supermix for Residual DNA Quantification. Both assay and supermix are guaranteed free of contaminating DNA.
The Residual DNA Quantification Kits are optimized to enable
- Highly precise, femtogram-level quantification of residual CHO or E. coli DNA
- Direct quantification without DNA purification steps
- Compatible with Bio-Rad’s QX100™, QX200™, or QX200™ AutoDG™ Droplet Digital PCR Systems