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| Packaging plays a critical role in ensuring the stability, safety, and efficacy of viral vector-based gene therapies. Key considerations include container closure integrity, low chemical reactivity, minimal extractables and leachables, reduced surface adsorption, and particulate control, particularly during ultra-low-temperature storage. Cyclic Olefin Polymer (COP) CZ vials address these challenges through high inertness, robust integrity, and compatibility with modern fill-finish processes, making them a reliable containment solution for advanced gene therapy products. Learn more |
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| | | This segment of Cell & Gene Live features Omkar Kawalekar, Ph.D., MFG & SC Lead, Deloitte Consulting, and Zoe Zheng, ED, Pipeline Technical and Strategic Lead, Legend Biotech, sharing what CGT developers should look for in a CDMO partnership, including transparency, data visibility, and capability rather than just capacity. CGT companies should retain deep product knowledge, CMC strategy, quality oversight, and regulatory understanding in-house. |
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| | | Scaling Commercial AAV Production Using Stable Producer Cell Lines | Poster | By Gang Li, Chien-Ting Li, Khanh Ho, Friedrich Michael Haller, et al., Lonza | Streamline your scale-up with helper-virus-free cell lines. Cultivated in suspension using chemically defined, serum-free medium, see how this method optimizes yields for commercial manufacturing. |
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| | | A Platform For Advanced AAV Analytics | Article | Andelyn Biosciences | Advanced AAV analytics use high‑resolution multiplex platforms to assess genome integrity and capsid traits, improving accuracy, speeding development, and supporting regulatory quality control. |
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| | | | Circular Single-Stranded Cell-Free DNA For Next-Gen Gene Editing | White Paper | By Mitchell Brun, Ph.D., Lisa Caproni, Ph.D., and Milica Vukovic, Ph.D., MBA, Touchlight | Next‑gen circular DNA payloads enhance gene insertion by improving stability, lowering cytotoxicity, and enabling precise, scalable integration across HDR, recombination, and transposition systems. |
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| The Cell & Gene Meeting on the Mesa is the sector’s premier annual conference, bringing together more than 1,500 industry leaders to address the key challenges facing cell and gene therapy commercialization. Featuring expert-led panels, extensive partnering opportunities, and 100+ company presentations, the meeting facilitates over 5,000 one-on-one meetings and showcases the latest clinical and commercial advances shaping the future of advanced therapies. |
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